一名出现反复腰痛的 27 岁女性体内的多发性骨髓瘤

Sandoval Correa Santiago, Mercado Valero Silvia Selene, Roberto de Jesús Martínez Camacho, Ruiz Gómez María Fernanda, Caldera Gonzalez Valeria Guadalupe, Ovalle Robles Itzel, Flores Hernandez Gilberto, Luis Carlos Caporal Trejo, Hayil Linaldi Sierra, Nieves Paredes Eduardo
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引用次数: 0

摘要

多发性骨髓瘤或卡勒氏病是一种以骨髓浆细胞增殖为特征的肿瘤,最常见的临床表现包括继发于骨溶解的骨痛、肾损伤和高钙血症。与这种病变相关的最常见风险因素包括高龄、多发性骨髓瘤家族史、酗酒、吸烟等。诊断方法包括通过电泳在血清和尿液中发现单克隆蛋白或副蛋白、在 24 小时尿液中发现游离链蛋白以及在血清中进行免疫固定。我们介绍了一例 27 岁女性患者的临床病例,她以腰痛为首发症状,在要求进行实验室检查时发现了与骨髓瘤相符的改变。经化验确诊为多发性骨髓瘤卡帕期ISS-III,目前正在接受环磷酰胺、地塞米松和沙利度胺治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multiple Myeloma in a 27-Year-Old Female Presenting with Recurrent Low Back Pain
Multiple Myeloma or Kahler's disease is a neoplasm characterized by proliferation of plasma cells in bone marrow where the most common clinical manifestations include bone pain secondary to osteolysis, kidney damage and hypercalcemia. The most common risk factors associated with this pathology are advanced age, family history of multiple myeloma, alcoholism, smoking, among others. Diagnosis includes the presence of monoclonal protein or paraprotein in serum and urine by electrophoresis, presence of free chain protein in 24-hour urine and immunofixation in serum. We present a clinical case of a 27-year-old female patient who presented lumbar pain as the initial manifestation and on requesting laboratory tests showed alterations compatible with myeloma. Laboratory studies were requested confirming the diagnosis of Multiple Myeloma kappa stage ISS-III in current treatment with cyclophosphamide, dexamethasone and thalidomide.
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