Ola Abdoalnasir Abdoalrasol Abdallah, Hafsa Ahmed Elrheima Ahmed
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引用次数: 0
摘要
背景:II 型糖尿病是一种慢性高血糖疾病。维生素 D 似乎与慢性疾病的预防和免疫调节有关。本研究旨在将维生素 D 水平与喀土穆州 2 型糖尿病患者的血糖控制联系起来。 研究方法这是一项前瞻性病例对照研究,于 2021 年 6 月至 11 月在苏丹喀土穆进行。共有 80 人参与研究,其中 40 人患有 2 型糖尿病,另外 40 人则是表面上健康的正常人。研究人员通过酶联免疫吸附法测定维生素 D。 研究结果使用 SPSS 进行统计分析。结果显示,病例组(糖尿病患者)中有 20% 的人维生素 D 水平不达标,而 80% 的人缺乏维生素 D。与对照组相比,病例组的维生素 D 水平明显下降(P 值 = 0.00)。糖化血红蛋白与维生素 D 水平呈负相关(P 值 = 0.017,R = -0.376)。 结论在这项研究中,2 型糖尿病患者的维生素 D 水平明显下降。血红蛋白 A1C 与维生素 D 水平呈弱负相关,不同性别和不同治疗类型的维生素 D 水平无明显差异。
Assessment of Vitamin D Level and Its Relation to Glycemic Control Among Patients with Type 2 Diabetes Mellitus in Khartoum State
Background: Type II diabetes is a chronic hyperglycemic disorder. Vitamin D appears to be associated with chronic disease prevention and modulation of immunity. This study was designed to associate vitamin D levels with glycemic control among type 2 diabetes mellitus in Khartoum state. Methods: This was a prospective case-control study conducted between June and November 2021 in Khartoum, Sudan. In total, 80 individuals were included in the study, of which 40 had type 2 diabetes mellitus, while the other 40 were normal, apparently healthy individuals. Vitamin D was measured by ELISA. Results: SPSS was used for statistical analysis. Results showed that 20% of the case group (patients with diabetes mellitus) had suboptimal vitamin D levels, whereas 80% had vitamin D deficiency. Vitamin D levels were significantly decreased among the case group when compared to the control group (P-value = 0.00). The glycated hemoglobin was negatively correlated with vitamin D level (P-value = 0.017, R = –0.376). Conclusion: In this study, a significant decrease in vitamin D was seen among people with type 2 DM. There was a weak negative correlation between hemoglobin A1C and vitamin D levels, and no significant difference in Vitamin D levels among gender and different types of treatment.