使乳牙萌出面临挑战的婴儿口腔微生物群恢复正常的机会

L. P. Kiselnikova, V. Tsarev, F. M. Balaphendieva, M. Podporin, P. K. Borodina
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摘要

相关性。儿童乳牙萌出是一个独特的生理过程,以局部和全身表现以及口腔微生物群的改变为特征。进行一项比较临床研究,评估不同药物在应对乳牙萌出挑战过程中处理局部症状的疗效,同时评估顺势疗法药物对儿童口腔微生物群的影响(体外)。研究对象包括 120 名 5 个月至 2 岁的婴儿,他们被随机分为三组(每组 40 人),均经历了具有挑战性的乳牙萌出期。研究组被分配了以下干预措施:一种顺势疗法药物、一种含有杀菌和镇痛特性的牙科凝胶,以及一种添加了植物提取物的牙科凝胶。采用 E.M. Kuzmina 指数(2000 年)对儿童进行了临床评估,同时还对口腔微生物群进行了评估。服用顺势疗法药剂后,根据 E.M. Kuzmina 指数,牙龈状况显示口腔卫生良好,而含有合成和植物杀菌剂和麻醉剂的药剂则显示口腔卫生水平令人满意。微生物学研究表明,使用所调查的顺势疗法药物样本有助于创造条件,促进稳定口腔微生物与致病微生物群的间接竞争。顺势疗法药物对乳牙萌出的临床疗效显著提高。每天两次使用顺势疗法药液后,儿童的口腔微生物群呈现出更显著的积极趋势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The opportunities for normalizing oral microbiota in infants with challenging deciduous teeth eruption
Relevance. The eruption of deciduous teeth is a distinct physiological process marked by local and systemic manifestations, along with alterations in oral microbiota in children.Research objective. A comparative clinical study evaluating the efficacy of different medications in managing localized symptoms during challenging deciduous teeth eruption, alongside an assessment of a homeopathic medicine's influence on oral microbiota in children (in vitro).Material and methods. The study encompassed 120 infants ranging from 5 months to 2 years old, randomized into three groups (40 individuals per group), all experiencing challenging deciduous teeth eruption. The research groups were assigned the following interventions: a homeopathic medicine, a dental gel containing an antiseptic and analgesic properties, and a dental gel infused with plant extracts. Clinical assessments of the children were performed using the E.M. Kuzmina index (2000), while concurrent evaluations of the oral microbiota were also conducted.Results. After the course of the medicinal homeopathic preparation, the condition of the gums, as per the E.M. Kuzmina index, indicated good oral hygiene, in contrast to medicinal preparations containing synthetic and plant-based antiseptics and anesthetics, which resulted in a satisfactory level of oral hygiene. Microbiological research indicated that the utilization of the investigated samples of the homeopathic medicine facilitated the creation of conditions fostering indirect competition of the stabilizing oral micro versus the pathogenic group of microorganisms.Conclusion. The clinical effectiveness of the homeopathic medicine for challenging deciduous teeth eruption was notably higher. A more substantial positive trend was observed in relation to the oral microbiota in children following the twice-daily application of the homeopathic medicine solution.
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