{"title":"分析 Kushta amruthasangadi avachurnana 及其改良马拉哈拉形式抗菌活性的研究","authors":"Saimeera P, Chithra G. Nair","doi":"10.55218/jasr.2023141106","DOIUrl":null,"url":null,"abstract":"Ayurveda categorizes various skin diseases under “kushta”, with treatments described in ancient texts like the Charaka samhitha. Among these treatments, kushtaamruthasangadi avachurnana (dusting powder) is recommended for skin conditions like dadru (tinea), kitibha (psoriasis), pama (scabies), and vicharchika (eczema), which exhibit itching, oozing, and discolouration. Avachurnana involves dusting fine powdered herbs over skin lesions. The avachurnana (dusting powder) formulation is having kushta (Saussurialappa) and amruthasanga (blue vitriol) as the first two ingredients; hence it is named as kushta amruthasangadi avachurnana. To enhance its effectiveness, this study explores transforming avachurnana (dusting powder) into a Malahara (oinment) to increase its contact duration on the skin. The research focuses on the antimicrobial properties of kushtaamruthasangadi avachurnana (dusting powder) and its Malahara (oinment) form by using agar well diffusion method against the strains streptococcus pyogens, staphylococcus aureus, aspergillus niger and candida albicans. In testing, avachurnana exhibited limited antimicrobial activity, with no impact on staphylococcus aureus and streptococcus pyogenes but showing inhibition of candida albicans. The Malahara form, tested 80% hexane, showed no impact on aspergillus niger and candida albicans but displayed some inhibition of staphylococcus aureus and streptococcus pyogens. The results suggest varying antimicrobial effectiveness against different microorganisms. Avachurnana is more potent against fungi like candida albicans and aspergillus niger, while the Malahara form shows some activity against specific bacteria. This difference could be due to the presence of sarshapataila in the Malahara, known for its antibacterial properties. In summary, this research investigates Ayurvedic treatments for skin diseases, shedding light on their antimicrobial effects and potential applications.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":" 21","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A STUDY TO ANALYSE THE ANTIMICROBIAL ACTIVITY OF KUSHTA AMRUTHASANGADI AVACHURNANA AND ITS MODIFIED MALAHARA FORM\",\"authors\":\"Saimeera P, Chithra G. Nair\",\"doi\":\"10.55218/jasr.2023141106\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ayurveda categorizes various skin diseases under “kushta”, with treatments described in ancient texts like the Charaka samhitha. Among these treatments, kushtaamruthasangadi avachurnana (dusting powder) is recommended for skin conditions like dadru (tinea), kitibha (psoriasis), pama (scabies), and vicharchika (eczema), which exhibit itching, oozing, and discolouration. Avachurnana involves dusting fine powdered herbs over skin lesions. The avachurnana (dusting powder) formulation is having kushta (Saussurialappa) and amruthasanga (blue vitriol) as the first two ingredients; hence it is named as kushta amruthasangadi avachurnana. To enhance its effectiveness, this study explores transforming avachurnana (dusting powder) into a Malahara (oinment) to increase its contact duration on the skin. The research focuses on the antimicrobial properties of kushtaamruthasangadi avachurnana (dusting powder) and its Malahara (oinment) form by using agar well diffusion method against the strains streptococcus pyogens, staphylococcus aureus, aspergillus niger and candida albicans. In testing, avachurnana exhibited limited antimicrobial activity, with no impact on staphylococcus aureus and streptococcus pyogenes but showing inhibition of candida albicans. The Malahara form, tested 80% hexane, showed no impact on aspergillus niger and candida albicans but displayed some inhibition of staphylococcus aureus and streptococcus pyogens. The results suggest varying antimicrobial effectiveness against different microorganisms. Avachurnana is more potent against fungi like candida albicans and aspergillus niger, while the Malahara form shows some activity against specific bacteria. This difference could be due to the presence of sarshapataila in the Malahara, known for its antibacterial properties. In summary, this research investigates Ayurvedic treatments for skin diseases, shedding light on their antimicrobial effects and potential applications.\",\"PeriodicalId\":14906,\"journal\":{\"name\":\"Journal of Advanced Scientific Research\",\"volume\":\" 21\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advanced Scientific Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55218/jasr.2023141106\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55218/jasr.2023141106","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A STUDY TO ANALYSE THE ANTIMICROBIAL ACTIVITY OF KUSHTA AMRUTHASANGADI AVACHURNANA AND ITS MODIFIED MALAHARA FORM
Ayurveda categorizes various skin diseases under “kushta”, with treatments described in ancient texts like the Charaka samhitha. Among these treatments, kushtaamruthasangadi avachurnana (dusting powder) is recommended for skin conditions like dadru (tinea), kitibha (psoriasis), pama (scabies), and vicharchika (eczema), which exhibit itching, oozing, and discolouration. Avachurnana involves dusting fine powdered herbs over skin lesions. The avachurnana (dusting powder) formulation is having kushta (Saussurialappa) and amruthasanga (blue vitriol) as the first two ingredients; hence it is named as kushta amruthasangadi avachurnana. To enhance its effectiveness, this study explores transforming avachurnana (dusting powder) into a Malahara (oinment) to increase its contact duration on the skin. The research focuses on the antimicrobial properties of kushtaamruthasangadi avachurnana (dusting powder) and its Malahara (oinment) form by using agar well diffusion method against the strains streptococcus pyogens, staphylococcus aureus, aspergillus niger and candida albicans. In testing, avachurnana exhibited limited antimicrobial activity, with no impact on staphylococcus aureus and streptococcus pyogenes but showing inhibition of candida albicans. The Malahara form, tested 80% hexane, showed no impact on aspergillus niger and candida albicans but displayed some inhibition of staphylococcus aureus and streptococcus pyogens. The results suggest varying antimicrobial effectiveness against different microorganisms. Avachurnana is more potent against fungi like candida albicans and aspergillus niger, while the Malahara form shows some activity against specific bacteria. This difference could be due to the presence of sarshapataila in the Malahara, known for its antibacterial properties. In summary, this research investigates Ayurvedic treatments for skin diseases, shedding light on their antimicrobial effects and potential applications.