分析 Kushta amruthasangadi avachurnana 及其改良马拉哈拉形式抗菌活性的研究

Saimeera P, Chithra G. Nair
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摘要

阿育吠陀将各种皮肤病归入 "kushta",并在 Charaka samhitha 等古籍中描述了治疗方法。在这些治疗方法中,kushtaamruthasangadi avachurnana(撒粉)被推荐用于治疗皮肤病,如dadru(癣)、kitibha(银屑病)、pama(疥疮)和vicharchika(湿疹),这些皮肤病表现出瘙痒、渗出和变色。Avachurnana 是将草药细粉撒在皮损处。avachurnana(粉末)配方的前两种成分是 kushta(Saussurialappa)和 amruthasanga(蓝矾),因此被命名为 kushta amruthasangadi avachurnana。为了提高其功效,本研究探讨了将 avachurnana(粉末)转化为 Malahara(油膏),以增加其在皮肤上的接触时间。研究重点是通过琼脂井扩散法,研究 kushtaamruthasangadi avachurnana(粉末)及其 Malahara(油膏)对化脓性链球菌、金黄色葡萄球菌、黑曲霉和白色念珠菌的抗菌特性。在测试中,avachurnana 表现出有限的抗菌活性,对金黄色葡萄球菌和化脓性链球菌没有影响,但对白色念珠菌有抑制作用。在 80% 的正己烷中测试的马拉哈拉形态对黑曲霉和白色念珠菌没有影响,但对金黄色葡萄球菌和化脓性链球菌有一定的抑制作用。结果表明,对不同微生物的抗菌效果各不相同。Avachurnana 对白色念珠菌和黑曲霉等真菌更有效,而马拉哈拉则对特定细菌有一定的活性。造成这种差异的原因可能是马拉哈拉中含有以抗菌著称的沙棘属植物。总之,这项研究调查了阿育吠陀治疗皮肤病的方法,揭示了它们的抗菌效果和潜在应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A STUDY TO ANALYSE THE ANTIMICROBIAL ACTIVITY OF KUSHTA AMRUTHASANGADI AVACHURNANA AND ITS MODIFIED MALAHARA FORM
Ayurveda categorizes various skin diseases under “kushta”, with treatments described in ancient texts like the Charaka samhitha. Among these treatments, kushtaamruthasangadi avachurnana (dusting powder) is recommended for skin conditions like dadru (tinea), kitibha (psoriasis), pama (scabies), and vicharchika (eczema), which exhibit itching, oozing, and discolouration. Avachurnana involves dusting fine powdered herbs over skin lesions. The avachurnana (dusting powder) formulation is having kushta (Saussurialappa) and amruthasanga (blue vitriol) as the first two ingredients; hence it is named as kushta amruthasangadi avachurnana. To enhance its effectiveness, this study explores transforming avachurnana (dusting powder) into a Malahara (oinment) to increase its contact duration on the skin. The research focuses on the antimicrobial properties of kushtaamruthasangadi avachurnana (dusting powder) and its Malahara (oinment) form by using agar well diffusion method against the strains streptococcus pyogens, staphylococcus aureus, aspergillus niger and candida albicans. In testing, avachurnana exhibited limited antimicrobial activity, with no impact on staphylococcus aureus and streptococcus pyogenes but showing inhibition of candida albicans. The Malahara form, tested 80% hexane, showed no impact on aspergillus niger and candida albicans but displayed some inhibition of staphylococcus aureus and streptococcus pyogens. The results suggest varying antimicrobial effectiveness against different microorganisms. Avachurnana is more potent against fungi like candida albicans and aspergillus niger, while the Malahara form shows some activity against specific bacteria. This difference could be due to the presence of sarshapataila in the Malahara, known for its antibacterial properties. In summary, this research investigates Ayurvedic treatments for skin diseases, shedding light on their antimicrobial effects and potential applications.
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