Evaluation of the physical properties and antibacterial effects on Candida albicans of denture base resin containing silver sulfadiazine

Objectives: The purpose of this study was to evaluate the physical properties and antibacterial activity of denture base resin with added silver sulfadiazine. Methods: Specimens were made from self-curing denture base resin and silver sulfadiazine as an inorganic antibacterial agent. For physical evaluation of the specimens, surface roughness, surface hardness, and contact angle were measured. Bacterial growth was assessed by optical densityat 600 nm (OD600) and colony forming units (CFU) measurements to confirm antibacterial activity. Results: There was no significant difference in surface roughness, surface hardness, and contact angle in the experimental group containing silver sulfadiazine compared to the control group. In contrast, the experimental group showed a significant decrease in antibacterial activity compared to the control group in terms of OD value. Analysis of CFU confirmed a significant decrease in colonies in the experimental group compared to the control group. Conclusions: Denture base resin containing silver sulfadiazine, an inorganic antibacterial agent, exhibited enhanced antibacterial activity without physical changes. In conclusion, the use of denture base resin containing inorganic antibacterial agents may be expected in the future.