咽扁桃体肥大患儿的临床和形态特征以及输卵管环的评估

Kateryna V. Lyakh, Serhii P. Luhovskyi, Anatoliy L. Kosakovskyi, Y. Shkorbotun, Mykola A. Skoryk
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摘要

简介在接受腺样体切除术的咽扁桃体肥大患儿中,有 31.3% 的病例即使没有中耳病变,也会表现出小管环肥大。然而,这些儿童这一解剖区域的变化性质尚未得到描述。 研究目的:调查和评估咽扁桃体肥大患儿咽扁桃体和小管环的形态变化。 材料和方法:对 12 名鼻腔呼吸障碍儿童(第 1 组)和 13 名伴有上呼吸道炎症疾病的儿童(第 2 组)在腺样体切除术中获得的咽扁桃体和输卵管环碎片进行组织学检查和扫描电子显微镜检查。 结果显示与第 1 组患者相比,第 2 组患者的咽扁桃体变化更明显,显示出炎症性改变,如覆盖上皮和上皮下层的多形核白细胞浸润,以及覆盖上皮的淋巴细胞,并伴有纤维化。 此外,与第 1 组患者相比,第 2 组患者的样本被生物膜覆盖的频率明显更高(53.8% 对 16.6%,P<0.05)。管状环的粘膜变化与各组咽扁桃体观察到的变化性质一致。第 2 组 38.5%的病例和第 1 组 8.3%的病例在输卵管样本中发现了生物膜(P<0.05)。 结论1.在咽扁桃体肥大和管状环肥大的儿童中,管状环粘膜的形态特征与各组咽扁桃体粘膜的形态特征相似。2.2. 与鼻呼吸障碍患者相比,上呼吸道感染患儿的咽扁桃体和管状结节表面更容易发现生物膜。3.检测到的变化为修订咽扁桃体肥大患儿肥大性小管环的治疗方法提供了依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CLINICAL AND MORPHOLOGICAL CHARACTERISTICS AND EVALUATION OF TORUS TUBARIUS IN CHILDREN WITH PHARYNGEAL TONSIL HYPERTROPHY
Introduction: Among children with hypertrophy of pharyngeal tonsils undergoing adenoidectomy, 31.3% of cases show hypertrophy of the torus tubarius, even in the absence of middle ear pathology. However, the nature of the changes in this anatomical area in these children has not been described. The aim of the study: to investigate and evaluate morphological changes of pharyngeal tonsil and torus tubarius in children with hypertrophy of pharyngeal tonsil. Materials and methods: histological investigation and scanning electron microscopy were performed on fragments of pharyngeal tonsil and torus tubarius, obtained during adenoidectomy of 12 children with nasal breathing disturbances (Group 1) and 13 children with concomitant inflammatory diseases of the upper respiratory tract (Group 2). Results: In patients of Group 2, changes in the pharyngeal tonsil were more pronounced, showing inflammatory alterations such as infiltration by polymorphonuclear leukocytes in the covering epithelium and subepithelial layer, as well as lymphocytes in the covering epithelium, along with the presence of fibrosis compared to patients of Group 1. Additionally, samples covered by biofilms were significantly more frequently identified in Group 2 compared to Group 1 (53.8% vs. 16.6%, p<0.05). The mucosal changes in the torus tubarius corresponded to the nature of the changes observed in the pharyngeal tonsil in the respective group. Biofilms in the torus tubarius samples were found in 38.5% of cases in Group 2 and 8.3% of cases in Group 1 (p<0.05). Conclusions: 1. In children with hypertrophy of pharyngeal tonsil and torus tubarius, the morphological characteristics of the mucous membrane of torus tubarius are similar to those observed in the mucous membrane of pharyngeal tonsil of the respective group. 2. Biofilms were reliably more frequently identified on the surface of pharyngeal tonsil and torus tubarius in children with upper respiratory tract infections than in patients with nasal breathing disturbances. 3. The detected changes provide a basis for revising the therapeutic approach to hypertrophic torus tubarius in children with pharyngeal tonsil hypertrophy.
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