J Katzhendler, G Bar-Ad, M Haran, K F Gean, Z Tashma, I Ringel, A Ramu, U Bachrach
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The effect of substituted aminoalkylaminoanthraquinones on eukaryotic cells.
Nine aminoalkylaminoanthraquinones (I-IX) were evaluated for their cytotoxic potency against normal and malignant mammalian cells. The 1.8-di-(aminopropylamino) derivative (VIII) exhibited significant activity against several tumor cell systems and had some selectivity. The toxicity of this compound was also tested in growing chick embryos.
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