黎巴嫩 Rhuh 地区 COVID-19 肺炎重症孕妇的治疗结果

El Mawla Zeinab
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摘要

导言:自宣布感染新型 COVID-19 以来,由于其巨大的发病率和死亡率,它一直是全世界关注的焦点,被视为国际公共卫生紧急事件。孕妇被认为是感染 SARS-COV2 的最易感人群,因此,对其风险因素、严重程度以及孕产妇和新生儿预后进行广泛研究,对于优化感染孕妇的治疗和管理至关重要。研究方法这是一项病例对照回顾性研究,研究对象是 2020 年 2 月至 2021 年 6 月期间在拉菲克-哈里里医院重症监护室住院的 COVID 感染女性患者(孕妇和非孕妇)。研究人员从数字化记录中收集数据,包括人口统计学特征、需氧量、生命体征、实验室结果、影像学、管理路线、孕产妇和新生儿结局。后者使用 SPSS 统计软件 19.0 版(纽约州阿蒙克:IBM 公司)进行分析。结果在疾病的严重程度、病程、住院时间、入住重症监护室、住院期间的并发症以及治疗方法等方面均无明显差异。非孕妇确实表现出更多的慢性疾病,主要是高血压和糖尿病,出现更严重的低氧血症,铁蛋白水平更高,入院时胸部 CT 显示肺部受累更多,并且主要使用肝素进行抗凝。新生儿死亡主要发生在妊娠终止且出院后缺乏随访的病例中。结论由于管理上的争议和证据的缺乏,孕妇住院治疗的适应症并不严重。两组孕妇的发病率和死亡率没有差异,因此需要进一步研究以优化治疗和预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes of Critically Ill Pregnant Women with COVID-19 Pneumonia at Rhuh in Lebanon
Introduction: Since its declaration, the novel COVID-19 has been the center stage of worldwide concern as an international public health emergency due to its immense morbidity and mortality. Pregnant women are considered the most vulnerable population when encountering a SARS-COV2 infection and so extensive studies regarding risk factors, level of severity as well as maternal & neonatal outcomes are crucial to optimize the approach and management of a pregnant infected female. Methods: This is a case-control retrospective study of women with COVID infection (pregnant and non-pregnant) admitted to ICU in Rafik Hariri Hospital between February 2020 and June 2021. Data were collected from digitized records including demographic characteristics, oxygen requirement, vitals, laboratory results, and imaging, management lines, maternal and neonatal outcomes. The latter was analyzed using SPSS Statistics Version 19.0, Armonk, NY: IBM Corp. Results: No significant difference was found concerning the severity of the disease and its course, length of hospital stay, ICU admission, complications during hospitalization, and treatment dministration. Non-pregnant women did exhibit more chronic illnesses, mainly HTN and DM, presented with more severe hypoxemia, higher ferritin levels, more lung involvement on CT chest on admission, and were primarily given heparin as anticoagulation. Neonatal death was significant in cases of pregnancy termination with a lack of follow-up after discharge. Conclusion: Pregnant women were hospitalized for less severe indications due to controversy on management and scarcity of evidence. No difference in morbidity and mortality between the two groups and further research is indicated for optimization of treatment and prognosis.
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