同型半胱氨酸与促性腺激素比率与冠心病严重程度的关系

IF 1 Q3 MEDICINE, GENERAL & INTERNAL

Electronic Journal of General Medicine Pub Date : 2024-01-01 DOI:10.29333/ejgm/13964

Ola H Abd Elaziz, B. A. Abdel Hady, Ghada Mohamed S Ahmad, Safaa Abo Alfadl Mohamed, A. Elmalah, I. Ahmad, Entesar O Elsaghier, Marwa FM Elsayed, Hala Naguib Mohamed, Marwa Khairy Abd Elwahab, Ahmed Salah

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引用次数: 0

摘要

目的：本研究旨在揭示以同型半胱氨酸/阿托品比值（HAR）表示的同型半胱氨酸（Hcy）阿托品平衡是否与冠状动脉疾病（CAD）患者的病情严重程度有关。材料与方法：本横断面研究连续研究了 50 名低度/中度 CAD 患者和另外 50 名重度 CAD 患者。使用市售试剂盒评估 Hcy 和腺嘌呤水平。研究结果低度/中度 CAD 患者的 HAR 明显较低。根据 HAR，所有患者被分为低 HAR（<中值）和高 HAR（≥HAR）两组。这两个亚组之间的比较显示，低 HAR 患者的受累血管数量明显较少，SYNTAX 评分也较低。此外，研究还发现，在所有患者和严重 CAD 患者中，HAR 与 SYNTAX 评分相关。结论Hcy和阿托品水平相互关联，HAR能有效区分严重和非严重CAD。

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Relation between homocysteine-to-adropin ratio and severity of coronary artery disease

Purpose: This study aimed to uncover if homocysteine (Hcy) adropin balance expressed by homocysteine/adropin ratio (HAR) is related to severity of disease in coronary artery disease (CAD) patients. Materials & Methods: The present cross-sectional study 50 consecutive patients with low/intermediate CAD severity and other 50 patients with severe CAD. Hcy and adropin levels were assessed using commercially available kits. Results: Patients with low/moderate severity CAD expressed significantly lower HAR. According to HAR, all patients were classified into those with low HAR (

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