局部类固醇依赖/受损面部的孤立和综合临床及皮肤镜特征:印度中部的一项研究

Sanskriti Chauhan, Rochit Singhal, Vivek Choudhary, S. Rathoriya
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摘要

摘要 背景:外用类固醇依赖性/损伤性面部(TSDF)是指由于面部在无监督下或长期外用皮质类固醇激素而导致的面部皮肤半永久性或永久性损伤。皮肤镜作为一种无创、有效的技术被广泛应用于分析 TSDF 的即时或延迟特征。研究目的目的是评估临床诊断的 TSDF 病例的临床概况和皮肤镜特征。材料与方法:研究对象为 2021 年 4 月至 2022 年 9 月期间到皮肤病、性病和麻风病科就诊的 75 名临床症状和体征提示 TSDF 的患者。研究人员进行了详尽的病史采集、临床评估和皮肤镜检查,并在结构化问卷中记录了数据。结果68%的患者为女性,男女比例为 2.1:1。最常患病的年龄段为 26-35 岁(48%),平均年龄为 31.8 岁。最常用的外用类固醇激素是二丙酸倍氯米松 0.25%(33.33%),其次是丙酸氯倍他索 0.05%(29.33%)。最常见的临床表现是红斑伴色素沉着(74.66%),其次是红斑伴毛细血管扩张(34.66%)。最常见的皮肤镜观察结果是红色弥漫区域伴有血管(61.33%),红色弥漫区域伴有夸张的色素网(52%),以及簇状绒毛伴有白色绒毛(44%)。结论外用皮质类固醇激素是现代临床上常见的滥用药物,会导致多种症状,引起皮肤科的高度关注。皮肤镜在早期识别和确定 TSDF 方面起着重要的评估作用,此外还能确定损害的严重程度。关键字外用类固醇依赖性/损伤性面部(TSDF) 外用皮质类固醇 皮肤镜
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characterization of isolated and integrated clinical and dermoscopic features of topical steroid-dependent/damaged face: A study from central India
ABSTRACT Background: Topical steroid-dependent/damaged face (TSDF) is defined as semi-permanent or permanent damage to the skin of the face due to unsupervised or prolonged application of topical corticosteroids to the face. Dermoscopy is widely practiced as a non-invasive, effective technique to analyze the immediate or delayed features of TSDF. Objectives: The objective was to evaluate the clinical profile along with dermoscopic features of clinically diagnosed cases of TSDF. Materials and Methods: The study was conducted on seventy-five patients attending the Department of Dermatology, Venereology, and Leprosy between April 2021 and September 2022 with clinical symptoms and signs suggestive of TSDF. Thorough history taking, clinical evaluation, and dermoscopic examination were performed, and data was recorded in a structured proforma with a sixteen-point questionnaire. Results: Sixty-eight percent of the patients were females, yielding a female-to-male ratio of 2.1:1. The most frequently affected age group was 26–35 years (48%), with a mean age of 31.8 years. The most common topical steroid employed was beclomethasone dipropionate 0.25% (33.33%), followed by clobetasol propionate 0.05% (29.33%). The most common clinical findings observed were erythema with hyperpigmentation (74.66%), followed by erythema with telangiectasia (34.66%). The most often observed dermoscopic findings were red, diffuse areas with vessels (61.33%), red, diffuse areas with an exaggerated pigment network (52%), and clustered vellus hairs with white vellus hair (44%). Conclusion: Topical corticosteroids are commonly abused drugs seen in modern clinical practice, resulting in a plethora of symptoms and creating a paramount dermatological concern. Dermoscopy plays a cardinal evaluating role in the early discernment and establishment of TSDF besides determining the gravity of damage. Key words: Topical steroid-dependent/damaged face (TSDF), Topical corticosteroids, Dermoscopy
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