超越传统药物：探索新型和潜在的利什曼寄生虫胰硫还原酶（LmTr）抑制剂

Journal of Biomolecular Structure and Dynamics Pub Date : 2024-01-04 DOI:10.1080/07391102.2023.2300062

Muhammad Sarfraz, M. Afroz Bakht, Mohammed Sanad Alshammari, Mohammad Alrofaidi, Abdullah R. Alzahrani, Lina Eltaib, Syed Mohammed Basheeruddin Asdaq, Faris F. Aba Alkhayl, Abida, Mohd Imran

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摘要

胰硫还原酶能中和巨噬细胞内产生的活性氧以杀死寄生虫，它是利什曼原虫赖以生存的逃避策略之一......

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Beyond traditional medications: exploring novel and potential inhibitors of trypanothione reductase (LmTr) of Leishmania parasites

The trypanothione reductase enzyme, which neutralizes the reactive oxygen species produced inside the macrophages to kill the parasites, is one of the evasion strategies Leishmania uses to survive ...

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Journal of Biomolecular Structure and Dynamics

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