肠道微生物群在人体新陈代谢和炎症性疾病中的作用：聚焦老年人

IF 3 4区生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Annals of Microbiology Pub Date : 2024-01-03 DOI:10.1186/s13213-023-01744-5

Mansoor Khaledi, Behnam Poureslamfar, Hashem O. Alsaab, Shahrad Tafaghodi, Ahmed Hjazi, Rajesh Singh, Ahmed Hussien Alawadi, Ali Alsaalamy, Qutaiba A. Qasim, Fatemeh Sameni

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引用次数: 0

摘要

在衰老过程中，肠道微生物群在调节宿主的免疫反应方面发挥着至关重要的作用。肠道微生物菌群失调与衰老、抗生素暴露、潜在疾病、感染、荷尔蒙变化、昼夜节律和营养不良等因素有关，这些因素可以单独存在，也可以共同存在。适当使用益生元和益生菌或许可以预防或减少这种紊乱。本综述的重点是整个生命周期中的肠道微生物群组成、影响肠道微生物群随衰老而变化的因素以及调节肠道微生物群的干预措施。

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The role of gut microbiota in human metabolism and inflammatory diseases: a focus on elderly individuals

The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by a different abundance of bacteria in several age groups. Gut microbiota dysbiosis is associated with aging, antibiotic exposure, underlying diseases, infections, hormonal variations, circadian rhythm, and malnutrition, either singularly or in combination. The appropriate use of prebiotics and probiotics may be able to prevent or reduce this disruption. The current review focuses on the gut microbiota composition across the life cycle, factors affecting gut microbiota changes with aging, and interventions to modulate gut microbiota.

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来源期刊

Annals of Microbiology 生物-生物工程与应用微生物

CiteScore

6.40

自引率

0.00%

发文量

审稿时长

3.2 months

期刊介绍： Annals of Microbiology covers these fields of fundamental and applied microbiology: general, environmental, food, agricultural, industrial, ecology, soil, water, air and biodeterioration. The journal’s scope does not include medical microbiology or phytopathological microbiology. Papers reporting work on bacteria, fungi, microalgae, and bacteriophages are welcome. Annals of Microbiology publishes Review Articles, Original Articles, Short Communications, and Editorials. Originally founded as Annali Di Microbiologia Ed Enzimologia in 1940, Annals of Microbiology is an official journal of the University of Milan.