乳房黑色素瘤：诊断难题。

IF 2.5 3区工程技术 Q2 BIOLOGY

Yale Journal of Biology and Medicine Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI:10.59249/WPKX7733

Marita A John, Niloufar Pourfarrokh, Jaya Ruth Asirvatham

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引用次数: 0

摘要

乳腺转移瘤虽然罕见，但在临床、放射学和组织病理学上都可以模仿原发肿瘤。黑色素瘤是一种转移性很强的肿瘤，被称为肿瘤的 "模仿者"。乳房转移性黑色素瘤可与原发性乳腺癌相似，给诊断带来挑战。在大多数病例中，它伴有播散性疾病，预后较差，因此，组织学、免疫组化和临床相关性是诊断这些病例的关键。在本病例报告中，我们讨论了一名 63 岁女性疑似乳腺癌的临床特征，介绍了免疫组化工作，并讨论了解读中的误区。

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Melanoma in the Breast: A Diagnostic Challenge.

Although rare, breast metastases can mimic primary tumors, both clinically, radiologically, and histopathologically. Melanoma is a highly metastasizing tumor, and it is known as a great mimicker of tumors. Metastatic melanoma in the breast can mimic primary breast cancer and pose a diagnostic challenge. In most cases, it is associated with disseminated disease and a poor prognosis, therefore, histologic, immunohistochemical and clinical correlation is crucial in diagnosing these cases. In this case report, we discuss a 63-year-old female who presented with clinical features of probable breast cancer, describe immunohistochemistry workup, and discuss pitfalls in interpretation.

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来源期刊

Yale Journal of Biology and Medicine Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology

CiteScore

5.00

自引率

0.00%

发文量

期刊介绍： The Yale Journal of Biology and Medicine (YJBM) is a graduate and medical student-run, peer-reviewed, open-access journal dedicated to the publication of original research articles, scientific reviews, articles on medical history, personal perspectives on medicine, policy analyses, case reports, and symposia related to biomedical matters. YJBM is published quarterly and aims to publish articles of interest to both physicians and scientists. YJBM is and has been an internationally distributed journal with a long history of landmark articles. Our contributors feature a notable list of philosophers, statesmen, scientists, and physicians, including Ernst Cassirer, Harvey Cushing, Rene Dubos, Edward Kennedy, Donald Seldin, and Jack Strominger. Our Editorial Board consists of students and faculty members from Yale School of Medicine and Yale University Graduate School of Arts & Sciences. All manuscripts submitted to YJBM are first evaluated on the basis of scientific quality, originality, appropriateness, contribution to the field, and style. Suitable manuscripts are then subject to rigorous, fair, and rapid peer review.