Dongsheng Tao, Wen Sun, Donghui Mo, Yonghui Lin, Wei Lv, Daniel Mmereki, Yousheng Xu, Yanghui Ye, Yuanjun Tang, Chao Ye, Cong Dong, Zhongming Bu
{"title":"减少中国家庭和幼儿园中儿童接触邻苯二甲酸二(2-乙基己酯)的机会:对终生癌症风险和疾病负担的影响","authors":"Dongsheng Tao, Wen Sun, Donghui Mo, Yonghui Lin, Wei Lv, Daniel Mmereki, Yousheng Xu, Yanghui Ye, Yuanjun Tang, Chao Ye, Cong Dong, Zhongming Bu","doi":"10.1007/s12273-023-1094-1","DOIUrl":null,"url":null,"abstract":"<p>Exposure to di(2-ethylhexyl) phthalate (DEHP) in the indoor environment has been linked with significant health risks for Chinese children. Multi-phase DEHP concentrations in Chinese residences and kindergartens were estimated using a mass balance model based on the current baseline condition and control strategies (i.e., increasing ventilation rate, reducing area of sources, using mechanical ventilation systems, and using portable air cleaners). The health benefits of each control strategy were quantified as the reduction in lifetime cancer risks (LCR) and burden of disease (BoD). In the current situation, the mean LCR and disability-adjusted life years (DALY) number attributable to indoor DEHP exposure for Chinese children were around 6.0×10<sup>−6</sup> and 155 thousand, respectively. The mean LCR and DALY might be reduced by 25%–54% and 16%–40%, respectively, by increasing air exchange rates by 100%, reducing the use of source materials by two-thirds or deploying commercial air cleaners in naturally ventilated buildings. Meanwhile, avoidable DALYs could result in a reduction of mean economic losses of 2.2–5.3 billion RMB. Mechanical ventilation systems with filtration units may not be helpful for reducing children’s health risks. House-specific and tailor-made control measures are critical in lowering indoor exposure to DEHP to promote sustainable buildings and children’s health in China.</p>","PeriodicalId":49226,"journal":{"name":"Building Simulation","volume":"81 1","pages":""},"PeriodicalIF":6.1000,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reducing children’s exposure to di(2-ethylhexyl) phthalate in homes and kindergartens in China: Impact on lifetime cancer risks and burden of disease\",\"authors\":\"Dongsheng Tao, Wen Sun, Donghui Mo, Yonghui Lin, Wei Lv, Daniel Mmereki, Yousheng Xu, Yanghui Ye, Yuanjun Tang, Chao Ye, Cong Dong, Zhongming Bu\",\"doi\":\"10.1007/s12273-023-1094-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Exposure to di(2-ethylhexyl) phthalate (DEHP) in the indoor environment has been linked with significant health risks for Chinese children. Multi-phase DEHP concentrations in Chinese residences and kindergartens were estimated using a mass balance model based on the current baseline condition and control strategies (i.e., increasing ventilation rate, reducing area of sources, using mechanical ventilation systems, and using portable air cleaners). The health benefits of each control strategy were quantified as the reduction in lifetime cancer risks (LCR) and burden of disease (BoD). In the current situation, the mean LCR and disability-adjusted life years (DALY) number attributable to indoor DEHP exposure for Chinese children were around 6.0×10<sup>−6</sup> and 155 thousand, respectively. The mean LCR and DALY might be reduced by 25%–54% and 16%–40%, respectively, by increasing air exchange rates by 100%, reducing the use of source materials by two-thirds or deploying commercial air cleaners in naturally ventilated buildings. Meanwhile, avoidable DALYs could result in a reduction of mean economic losses of 2.2–5.3 billion RMB. Mechanical ventilation systems with filtration units may not be helpful for reducing children’s health risks. House-specific and tailor-made control measures are critical in lowering indoor exposure to DEHP to promote sustainable buildings and children’s health in China.</p>\",\"PeriodicalId\":49226,\"journal\":{\"name\":\"Building Simulation\",\"volume\":\"81 1\",\"pages\":\"\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2023-12-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Building Simulation\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s12273-023-1094-1\",\"RegionNum\":1,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CONSTRUCTION & BUILDING TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Building Simulation","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s12273-023-1094-1","RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CONSTRUCTION & BUILDING TECHNOLOGY","Score":null,"Total":0}
Reducing children’s exposure to di(2-ethylhexyl) phthalate in homes and kindergartens in China: Impact on lifetime cancer risks and burden of disease
Exposure to di(2-ethylhexyl) phthalate (DEHP) in the indoor environment has been linked with significant health risks for Chinese children. Multi-phase DEHP concentrations in Chinese residences and kindergartens were estimated using a mass balance model based on the current baseline condition and control strategies (i.e., increasing ventilation rate, reducing area of sources, using mechanical ventilation systems, and using portable air cleaners). The health benefits of each control strategy were quantified as the reduction in lifetime cancer risks (LCR) and burden of disease (BoD). In the current situation, the mean LCR and disability-adjusted life years (DALY) number attributable to indoor DEHP exposure for Chinese children were around 6.0×10−6 and 155 thousand, respectively. The mean LCR and DALY might be reduced by 25%–54% and 16%–40%, respectively, by increasing air exchange rates by 100%, reducing the use of source materials by two-thirds or deploying commercial air cleaners in naturally ventilated buildings. Meanwhile, avoidable DALYs could result in a reduction of mean economic losses of 2.2–5.3 billion RMB. Mechanical ventilation systems with filtration units may not be helpful for reducing children’s health risks. House-specific and tailor-made control measures are critical in lowering indoor exposure to DEHP to promote sustainable buildings and children’s health in China.
期刊介绍:
Building Simulation: An International Journal publishes original, high quality, peer-reviewed research papers and review articles dealing with modeling and simulation of buildings including their systems. The goal is to promote the field of building science and technology to such a level that modeling will eventually be used in every aspect of building construction as a routine instead of an exception. Of particular interest are papers that reflect recent developments and applications of modeling tools and their impact on advances of building science and technology.