继发性腹部包虫病的化学预防——实验研究与临床观察。

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR Pub Date : 1989-01-01

G Stojanow, D Jurukowa, P Meinhard

{"title":"继发性腹部包虫病的化学预防——实验研究与临床观察。","authors":"G Stojanow, D Jurukowa, P Meinhard","doi":"","DOIUrl":null,"url":null,"abstract":"An experiment was carried out in white mice by intra-abdominal injection of protoscolices. A chemoprophylaxis of the secondary abdominal echinococcosis was practised by means of Mebendazole (Vermox) in a dosage of 50 mg/kg body weight daily for 90 days. The chemoprophylaxis started on the twentieth day after the infection. Three animal groups were divided: group 1--peroral application of the drug, group 2--injection of the drug, group 3--control group. The autopsy of the mice were carried out one month after the end of the chemoprophylaxis. An echinococcosis was diagnosable only in the control group. The application in one patient showed the same good result.","PeriodicalId":77647,"journal":{"name":"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR","volume":"22 3","pages":"180-3"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Chemoprevention of secondary abdominal echinococcosis--experimental study and clinical observation].\",\"authors\":\"G Stojanow, D Jurukowa, P Meinhard\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An experiment was carried out in white mice by intra-abdominal injection of protoscolices. A chemoprophylaxis of the secondary abdominal echinococcosis was practised by means of Mebendazole (Vermox) in a dosage of 50 mg/kg body weight daily for 90 days. The chemoprophylaxis started on the twentieth day after the infection. Three animal groups were divided: group 1--peroral application of the drug, group 2--injection of the drug, group 3--control group. The autopsy of the mice were carried out one month after the end of the chemoprophylaxis. An echinococcosis was diagnosable only in the control group. The application in one patient showed the same good result.\",\"PeriodicalId\":77647,\"journal\":{\"name\":\"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR\",\"volume\":\"22 3\",\"pages\":\"180-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

采用小鼠腹腔内注射原脊柱侧弯的方法进行了实验。继发性腹部棘球蚴病的化学预防方法是甲苯达唑(Vermox)，剂量为每天50 mg/kg体重，持续90天。感染后第20天开始进行化学预防。将动物分为三组:第1组口服给药，第2组注射给药，第3组为对照组。在化学预防结束一个月后对小鼠进行尸检。仅在对照组中诊断出棘球蚴病。在一个病人的应用显示了同样的好结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Chemoprevention of secondary abdominal echinococcosis--experimental study and clinical observation].

An experiment was carried out in white mice by intra-abdominal injection of protoscolices. A chemoprophylaxis of the secondary abdominal echinococcosis was practised by means of Mebendazole (Vermox) in a dosage of 50 mg/kg body weight daily for 90 days. The chemoprophylaxis started on the twentieth day after the infection. Three animal groups were divided: group 1--peroral application of the drug, group 2--injection of the drug, group 3--control group. The autopsy of the mice were carried out one month after the end of the chemoprophylaxis. An echinococcosis was diagnosable only in the control group. The application in one patient showed the same good result.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR

自引率

0.00%

发文量