Sylvia L Crowder, Xiaoyin Li, Caroline Himbert, Richard Viskochil, Aasha I Hoogland, Lisa M Gudenkauf, Laura B Oswald, Brian D Gonzalez, Brent J Small, Cornelia M Ulrich, Jennifer Ose, Anita R Peoples, Christopher I Li, David Shibata, Adetunji T Toriola, Biljana Gigic, Mary C Playdon, Sheetal Hardikar, Julienne Bower, Erin M Siegel, Jane C Figueiredo, Heather S L Jim
{"title":"体育锻炼、睡眠和癌症相关疲劳之间的关系：国际癌症护理研究的结果。","authors":"Sylvia L Crowder, Xiaoyin Li, Caroline Himbert, Richard Viskochil, Aasha I Hoogland, Lisa M Gudenkauf, Laura B Oswald, Brian D Gonzalez, Brent J Small, Cornelia M Ulrich, Jennifer Ose, Anita R Peoples, Christopher I Li, David Shibata, Adetunji T Toriola, Biljana Gigic, Mary C Playdon, Sheetal Hardikar, Julienne Bower, Erin M Siegel, Jane C Figueiredo, Heather S L Jim","doi":"10.1093/abm/kaad068","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Risk factors for cancer-related fatigue are understudied in colorectal cancer.</p><p><strong>Purpose: </strong>This study aimed to address this critical gap in the literature by (a) describing changes in colorectal cancer-related fatigue and health behavior (physical activity, sleep problems) and (b) examining if physical activity and sleep problems predict fatigue trajectories from baseline (approximately at the time of diagnosis), to 6- and 12 months after enrollment.</p><p><strong>Methods: </strong>Patients participating in the international ColoCare Study completed self-report measures at baseline (approximately time of diagnosis), 6-, and 12 months assessing physical activity using the International Physical Activity Questionnaire (IPAQ) and fatigue and sleep using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30). Mixed-effect models examined changes in physical activity, sleep problems, and fatigue. Cross-lagged panel models examined bidirectional relationships between physical activity or sleep and fatigue across time.</p><p><strong>Results: </strong>Colorectal cancer patients (n = 649) had a mean age of 61 ± 13 years. Most were male (59%), non-Hispanic White (91%), diagnosed with Stages III-IV (56%) colon cancer (58%), and treated with surgery (98%). Within-person cross-lagged models indicated higher physical activity at Month 6 was associated with higher fatigue at Month 12 (β = 0.26, p = .016). When stratified by cancer stage (I-II vs. III-IV), the relationship between physical activity at Month 6 and fatigue at Month 12 existed only for patients with advanced cancer (Stages III and IV, β = 0.43, p = .035). Cross-lagged associations for sleep and fatigue from baseline to Month 6 were only observed in patients with Stages III or IV cancer, however, there was a clear cross-sectional association between sleep problems and fatigue at baseline and Month 6.</p><p><strong>Conclusions: </strong>Within-person and cross-lagged association models suggest fatiguability may become increasingly problematic for patients with advanced colorectal cancer the first year after diagnosis. In addition, sleep problems were consistently associated with higher fatigue in the first year, regardless of cancer stage.</p><p><strong>Trial registration: </strong>The international ColoCare Study was registered on clinicaltrials.gov, NCT02328677, in December 2014.</p>","PeriodicalId":7939,"journal":{"name":"Annals of Behavioral Medicine","volume":" ","pages":"156-166"},"PeriodicalIF":3.6000,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858307/pdf/","citationCount":"0","resultStr":"{\"title\":\"Relationships Among Physical Activity, Sleep, and Cancer-related Fatigue: Results From the International ColoCare Study.\",\"authors\":\"Sylvia L Crowder, Xiaoyin Li, Caroline Himbert, Richard Viskochil, Aasha I Hoogland, Lisa M Gudenkauf, Laura B Oswald, Brian D Gonzalez, Brent J Small, Cornelia M Ulrich, Jennifer Ose, Anita R Peoples, Christopher I Li, David Shibata, Adetunji T Toriola, Biljana Gigic, Mary C Playdon, Sheetal Hardikar, Julienne Bower, Erin M Siegel, Jane C Figueiredo, Heather S L Jim\",\"doi\":\"10.1093/abm/kaad068\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Risk factors for cancer-related fatigue are understudied in colorectal cancer.</p><p><strong>Purpose: </strong>This study aimed to address this critical gap in the literature by (a) describing changes in colorectal cancer-related fatigue and health behavior (physical activity, sleep problems) and (b) examining if physical activity and sleep problems predict fatigue trajectories from baseline (approximately at the time of diagnosis), to 6- and 12 months after enrollment.</p><p><strong>Methods: </strong>Patients participating in the international ColoCare Study completed self-report measures at baseline (approximately time of diagnosis), 6-, and 12 months assessing physical activity using the International Physical Activity Questionnaire (IPAQ) and fatigue and sleep using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30). Mixed-effect models examined changes in physical activity, sleep problems, and fatigue. Cross-lagged panel models examined bidirectional relationships between physical activity or sleep and fatigue across time.</p><p><strong>Results: </strong>Colorectal cancer patients (n = 649) had a mean age of 61 ± 13 years. Most were male (59%), non-Hispanic White (91%), diagnosed with Stages III-IV (56%) colon cancer (58%), and treated with surgery (98%). Within-person cross-lagged models indicated higher physical activity at Month 6 was associated with higher fatigue at Month 12 (β = 0.26, p = .016). When stratified by cancer stage (I-II vs. III-IV), the relationship between physical activity at Month 6 and fatigue at Month 12 existed only for patients with advanced cancer (Stages III and IV, β = 0.43, p = .035). Cross-lagged associations for sleep and fatigue from baseline to Month 6 were only observed in patients with Stages III or IV cancer, however, there was a clear cross-sectional association between sleep problems and fatigue at baseline and Month 6.</p><p><strong>Conclusions: </strong>Within-person and cross-lagged association models suggest fatiguability may become increasingly problematic for patients with advanced colorectal cancer the first year after diagnosis. In addition, sleep problems were consistently associated with higher fatigue in the first year, regardless of cancer stage.</p><p><strong>Trial registration: </strong>The international ColoCare Study was registered on clinicaltrials.gov, NCT02328677, in December 2014.</p>\",\"PeriodicalId\":7939,\"journal\":{\"name\":\"Annals of Behavioral Medicine\",\"volume\":\" \",\"pages\":\"156-166\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2024-02-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10858307/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Behavioral Medicine\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1093/abm/kaad068\",\"RegionNum\":2,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHOLOGY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Behavioral Medicine","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1093/abm/kaad068","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}
Relationships Among Physical Activity, Sleep, and Cancer-related Fatigue: Results From the International ColoCare Study.
Background: Risk factors for cancer-related fatigue are understudied in colorectal cancer.
Purpose: This study aimed to address this critical gap in the literature by (a) describing changes in colorectal cancer-related fatigue and health behavior (physical activity, sleep problems) and (b) examining if physical activity and sleep problems predict fatigue trajectories from baseline (approximately at the time of diagnosis), to 6- and 12 months after enrollment.
Methods: Patients participating in the international ColoCare Study completed self-report measures at baseline (approximately time of diagnosis), 6-, and 12 months assessing physical activity using the International Physical Activity Questionnaire (IPAQ) and fatigue and sleep using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30). Mixed-effect models examined changes in physical activity, sleep problems, and fatigue. Cross-lagged panel models examined bidirectional relationships between physical activity or sleep and fatigue across time.
Results: Colorectal cancer patients (n = 649) had a mean age of 61 ± 13 years. Most were male (59%), non-Hispanic White (91%), diagnosed with Stages III-IV (56%) colon cancer (58%), and treated with surgery (98%). Within-person cross-lagged models indicated higher physical activity at Month 6 was associated with higher fatigue at Month 12 (β = 0.26, p = .016). When stratified by cancer stage (I-II vs. III-IV), the relationship between physical activity at Month 6 and fatigue at Month 12 existed only for patients with advanced cancer (Stages III and IV, β = 0.43, p = .035). Cross-lagged associations for sleep and fatigue from baseline to Month 6 were only observed in patients with Stages III or IV cancer, however, there was a clear cross-sectional association between sleep problems and fatigue at baseline and Month 6.
Conclusions: Within-person and cross-lagged association models suggest fatiguability may become increasingly problematic for patients with advanced colorectal cancer the first year after diagnosis. In addition, sleep problems were consistently associated with higher fatigue in the first year, regardless of cancer stage.
Trial registration: The international ColoCare Study was registered on clinicaltrials.gov, NCT02328677, in December 2014.
期刊介绍：
Annals of Behavioral Medicine aims to foster the exchange of knowledge derived from the disciplines involved in the field of behavioral medicine, and the integration of biological, psychosocial, and behavioral factors and principles as they relate to such areas as health promotion, disease prevention, risk factor modification, disease progression, adjustment and adaptation to physical disorders, and rehabilitation. To achieve these goals, much of the journal is devoted to the publication of original empirical articles including reports of randomized controlled trials, observational studies, or other basic and clinical investigations. Integrative reviews of the evidence for the application of behavioral interventions in health care will also be provided. .
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