以多发性骨溶解性病变为唯一表现的成人前体 B 细胞淋巴细胞淋巴瘤/白血病罕见病例

Q4 Medicine

Acta Medica Bulgarica Pub Date : 2023-12-01 DOI:10.2478/amb-2023-0044

I. Micheva, S. Dimitrova

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引用次数: 0

摘要

摘要骨原发性前体B淋巴细胞淋巴瘤/白血病（B-LBLL）是一种不常见的肿瘤，占原发性骨肿瘤的1%以下。它常见于儿童，但在成人中却很罕见。我们报告了一例 20 岁男性急性淋巴细胞白血病患者的病例，该患者以多发性溶骨性病变为唯一表现，通过骨活检确诊为急性淋巴细胞白血病。外周血涂片和骨髓穿刺检查均未发现胚泡细胞。患者接受了 BFM 99 方案的治疗，并经 F-FDG-PET/CT 证实获得了完全缓解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Rare Case of Adult Precursor B-Cell Lymphoblastic Lymphoma/Leukemia Presenting with Multiple Osteolytic Bone Lesions as Sole Manifestation

Abstract Primary precursor B-lymphoblastic lymphoma/leukemia (B-LBLL) of bone is uncommon neoplasm that accounts for less than 1% of primary bone tumors. It has been commonly reported in pediatric population but is rare in adults. We present a case of a 20-year-old man with multiple osteolytic lesions as sole presentation of acute lymphoblastic leukemia, whose diagnosis was established by bone biopsy. A peripheral blood smear and the bone marrow aspirate showed no blast cells. The patient received treatment according to BFM 99 protocol and achieved complete response confirmed by F-FDG-PET/CT.

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来源期刊

Acta Medica Bulgarica Medicine-Medicine (all)

CiteScore

0.30

自引率

0.00%

发文量

审稿时长

25 weeks

期刊介绍： About 30 years ago - in 1973, on the initiative of the Publishing House „Medicine and Physical Culture", namely its former director Mr. Traian Ivanov, the Ministry of Health set up and accepted to subsidize a new medical magazine that was to be published only in the English language and had to reflect the status and the achievements of the Bulgarian medical science. Thus the language barrier was overcome and stable relations were established with the international medical society, large libraries, and university centers. The famous internationally known scientist professor Assen A. Hadjiolov was elected edition-in-chief by the first editorial staff and the magazine was named Acta Medica Bulgarica.