原发性醛固酮过多症:选择保守手术

M. S. Annayev, K. Stegniy, B. Geltser, R. Goncharuk, A. M. Morozova, E. V. Maslyantsev
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引用次数: 0

摘要

原发性醛固酮增多症(PHA)是继发性动脉高血压最常见的内分泌疾病。 鉴于这种病症的患者发生致命性和非致命性心血管事件的风险较高,因此早期诊断和及时治疗非常重要。目前,PHA 的两种主要形式是醛固酮分泌腺瘤和双侧肾上腺增生症,治疗方法是进行腹腔镜肾上腺切除术或使用矿物皮质激素受体拮抗剂进行药物治疗。虽然大多数患者在手术治疗后功能和代谢状态得到恢复,但有些患者可能会出现术后肾上腺功能不全,需要长期激素替代治疗。本综述探讨了保留器官手术的选择,如肾上腺部分切除术和肾上腺动脉选择性栓塞术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Primary hyperaldosteronism: the choice in favor of conservative surgery
Primary hyperaldosteronism (PHA) is the most common cause of secondary arterial hypertension among endocrine disorders.  Given that patients with this pathology are at a higher risk of developing fatal and non-fatal cardiovascular events, early  diagnosis and timely treatment are of great importance. Currently, the two main forms of PHA are aldosterone-producing  adenoma and bilateral adrenal hyperplasia, which are treated with laparoscopic adrenalectomy or pharmacotherapy with  mineralocorticoid receptor antagonists. Although most patients experience restoration of their functional and metabolic  status after surgical intervention, some may develop postoperative adrenal insuffi ciency, which requires long-term hormone  replacement therapy. This review examines the options for organ-preserving surgeries, such as partial adrenalectomy and  selective embolization of the adrenal artery.
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