利用 Geant4/ Gate7 生成 18FDG 的新方法

Abuzar Shakeri, Ebrahim Heidari, Nasrin Hosseini Motlagh, H. Vanaei
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引用次数: 0

摘要

氟 18-脱氧葡萄糖常用于正电子发射断层扫描设备。正电子发射断层扫描成像是用于癌症检测和治疗的有用工具之一。由于氟-18 的生产问题,正电子发射断层成像技术的发展受到了限制。成像结果在很大程度上取决于核反应截面数据的信息。本研究旨在计算氟-18 在水中的不同数量,如停止功率、CSDA 范围、模拟吸收剂量和分布吸收剂量。为了实现这些目标,我们使用了 Geant4/Gate7 模拟和 Bethe-Bloch 模型。模拟结果与理论模型的结果非常吻合。本文的重点是介绍一种理论方法,以便利用主 D(d;p)T 和侧 3 He(d;p)4 He 核聚变反应产生的质子来生产氟-18,其中使用氦-3 作为催化剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Method for 18FDG generating using Geant4/ Gate7
Fluorine 18-deoxyglucose is often used in Positron Emission Tomography devices. Positron Emission Tomography imaging is one of the useful tool which is used for cancer detection and its management. Positron Emission Tomography growth is limited due to problems that depend on the production of Fluorine-18. Imaging results are strongly depending on the information of nuclear reaction cross section data. This study is presented to calculate different quantities such as stopping power, CSDA range, simulated and distributed absorbed dose of Fluorine-18 in water. In order to access these goals, we use Geant4/Gate7 simulation and the Bethe-Bloch model. The results of this simulation and theoretical model presented are in good agreement with each other. The important point of this paper is the presentation of a theoretical approach in order to the production of Fluorine-18 using protons generated through the main D(d;p)Tand side 3 He(d;p)4 He nuclear fusion reaction in which uses Helium-3 is catalyzed.
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