尼日利亚哈科特港大学教学医院就诊患者伤口分离菌的抗生素图谱

Isomah, C. J, Ogbonna, S. I., Robinson, V. K., Ogbuleka, N. A. C.
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引用次数: 0

摘要

伤口感染的风险随着污染程度的增加而增加,据估计,约有 50%受细菌污染的伤口会出现临床感染。本研究调查了从哈科特港大学教学医院(UPTH)就诊患者伤口感染中分离出的细菌概况。从男女患者身上采集了 108 个伤口分离菌,并在营养琼脂、麦康凯和血琼脂上进行培养。根据分离物的形态和生化特征,金黄色葡萄球菌 44(40.75%)是研究区男女患者伤口感染中最常见的细菌,其次是铜绿假单胞菌 28(25.9%)、克雷伯菌属 14(13.0%)、变形杆菌属 10(9.3%)和大肠埃希菌 12(11.1%)。抗生素图显示存在多重耐药菌。分离菌株的敏感性百分比为亚胺培南(80%)、庆大霉素(62%)、克林霉素(30%)和左氧氟沙星(30%)。因此,这些抗生素应被视为治疗该地区伤口的一线药物,因为它们是最有效的抗生素。因此,建议在出现伤口感染时及时进行治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiogram of Wound Isolates of Patients Attending University of Port Harcourt Teaching Hospital, Nigeria
The risk of wound infection increases with the degree of contamination and it has been estimated that about 50% of wounds contaminated with bacteria become clinically infected. Profile of bacteria isolated from wound infections in patients attending University of Port Harcourt teaching Hospital (UPTH) were investigated. One hundred and eight wound isolates were collected from male and female patients and cultured on nutrient agar, MacConkey and blood agar. Based on morphological and biochemical characteristics of the isolates, Staphylococcus aureus 44(40.75%) was the most prevalent in wound infection in the study area in both male and females followed by Pseudomonas aeruginosa 28(25.9%), Klebsiella spp. 14(13.0%), Proteus spp. 10(9.3%) and Escherichia coli 12(11.1%). The antibiogram showed the presence of multi-drug resistant organisms. The percentage susceptibility of the isolates was: Imipenem (80%), Gentamycin (62%) clindamycin (30%), and levofloxacin (30%). Thus, these antibiotics should be considered as first line drug in the treatment of wound in the area as they were the most effective antibiotics. Prompt and timely treatment is therefore, recommended on the onset of wound infections.
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