{"title":"Adichunchanagiri 医院 B.G Nagara 的产妇 ABO 血型与妊娠并发症的关系 - 一项横断面研究","authors":"Malini M, Meghana Cr, Amita K, Smitha N","doi":"10.18231/j.pjms.2023.146","DOIUrl":null,"url":null,"abstract":"ABO blood group has been divulged as a risk factor for perceptible diseased states. The ABO blood group differences may put a patient at specific risk according to their inherited antigens among the obstetrical syndromes like Intrauterine growth restriction, Pre-eclampsia and pre-term labour. Studies conducted have shown Group O individuals had lowest plasma von Willebrand factor and non O group had elevated level of this factor which showed increased thrombotic risk among these individuals. The earlier studies conducted have focused only on preeclampsia but not on other complications of pregnancy and the data available is scarce. The study aims to determine whether maternal ABO blood groups contribute to adverse pregnancy outcomes especially in this part of the country.The study was conducted on 50 pregnant women who were having complications of pregnancy including preeclampsia (PE), cases of Pregnancy induced hypertension (PIH), Gestational Diabetes mellitus (GDM) were considered as study cases and 50 pregnant women with normal pregnancy without any complications were categorized as controls. The study was conducted for a period of 6 months among patients attending Obstetrics and Gynecology department of Adichunchanagiri hospital selected based on convenience sampling procedure. Maternal ABO Blood group of the subjects were determined by Haemagglutination technique.Relationship between maternal ABO Blood group and Pregnancy complications (PE, PIH.GDM) was estimated by calculating odds ratio from logistic regression models using Blood Group O as a reference group and p – value of < 0.05 was considered as statistically significant. The results of the present study have found that maternal AB blood group was highest among preeclampsia and PIH category of cases.The present study conducted have found maternal AB blood group was highest among PIH and preeclampsia category of casesFrom the study conducted we want to conclude non-O blood group had the highest risk compared to O Blood group among pregnancy complications.","PeriodicalId":30643,"journal":{"name":"PANACEA JOURNAL OF MEDICAL SCIENCES","volume":"342 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship between Maternal ABO Blood group and pregnancy complications of adichunchanagiri hospital B.G Nagara -A cross sectional study\",\"authors\":\"Malini M, Meghana Cr, Amita K, Smitha N\",\"doi\":\"10.18231/j.pjms.2023.146\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABO blood group has been divulged as a risk factor for perceptible diseased states. The ABO blood group differences may put a patient at specific risk according to their inherited antigens among the obstetrical syndromes like Intrauterine growth restriction, Pre-eclampsia and pre-term labour. Studies conducted have shown Group O individuals had lowest plasma von Willebrand factor and non O group had elevated level of this factor which showed increased thrombotic risk among these individuals. The earlier studies conducted have focused only on preeclampsia but not on other complications of pregnancy and the data available is scarce. The study aims to determine whether maternal ABO blood groups contribute to adverse pregnancy outcomes especially in this part of the country.The study was conducted on 50 pregnant women who were having complications of pregnancy including preeclampsia (PE), cases of Pregnancy induced hypertension (PIH), Gestational Diabetes mellitus (GDM) were considered as study cases and 50 pregnant women with normal pregnancy without any complications were categorized as controls. The study was conducted for a period of 6 months among patients attending Obstetrics and Gynecology department of Adichunchanagiri hospital selected based on convenience sampling procedure. Maternal ABO Blood group of the subjects were determined by Haemagglutination technique.Relationship between maternal ABO Blood group and Pregnancy complications (PE, PIH.GDM) was estimated by calculating odds ratio from logistic regression models using Blood Group O as a reference group and p – value of < 0.05 was considered as statistically significant. The results of the present study have found that maternal AB blood group was highest among preeclampsia and PIH category of cases.The present study conducted have found maternal AB blood group was highest among PIH and preeclampsia category of casesFrom the study conducted we want to conclude non-O blood group had the highest risk compared to O Blood group among pregnancy complications.\",\"PeriodicalId\":30643,\"journal\":{\"name\":\"PANACEA JOURNAL OF MEDICAL SCIENCES\",\"volume\":\"342 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"PANACEA JOURNAL OF MEDICAL SCIENCES\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.pjms.2023.146\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"PANACEA JOURNAL OF MEDICAL SCIENCES","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.pjms.2023.146","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
ABO 血型被认为是可感知疾病状态的风险因素。ABO 血型的差异会根据患者的遗传抗原,使其在宫内发育受限、子痫前期和早产等产科综合症中面临特定风险。研究表明,O 组患者的血浆中冯-威廉因子含量最低,而非 O 组患者的血浆中冯-威廉因子含量较高,这表明这些患者的血栓风险增加。早期的研究只关注子痫前期,而没有关注妊娠期的其他并发症,而且可用数据很少。这项研究以 50 名患有妊娠并发症(包括子痫前期(PE)、妊娠高血压(PIH)、妊娠糖尿病(GDM))的孕妇为研究病例,50 名无任何并发症的正常妊娠孕妇为对照组。研究在阿迪春查纳吉里医院妇产科就诊的患者中进行,为期 6 个月,采用方便抽样程序。母体 ABO 血型与妊娠并发症(PE、PIH、GDM)之间的关系是通过以 O 型血为参照组的逻辑回归模型计算出的几率来估算的,P 值小于 0.05 视为具有统计学意义。本研究结果发现,在子痫前期和 PIH 类病例中,母体 AB 血型的风险最高。
Relationship between Maternal ABO Blood group and pregnancy complications of adichunchanagiri hospital B.G Nagara -A cross sectional study
ABO blood group has been divulged as a risk factor for perceptible diseased states. The ABO blood group differences may put a patient at specific risk according to their inherited antigens among the obstetrical syndromes like Intrauterine growth restriction, Pre-eclampsia and pre-term labour. Studies conducted have shown Group O individuals had lowest plasma von Willebrand factor and non O group had elevated level of this factor which showed increased thrombotic risk among these individuals. The earlier studies conducted have focused only on preeclampsia but not on other complications of pregnancy and the data available is scarce. The study aims to determine whether maternal ABO blood groups contribute to adverse pregnancy outcomes especially in this part of the country.The study was conducted on 50 pregnant women who were having complications of pregnancy including preeclampsia (PE), cases of Pregnancy induced hypertension (PIH), Gestational Diabetes mellitus (GDM) were considered as study cases and 50 pregnant women with normal pregnancy without any complications were categorized as controls. The study was conducted for a period of 6 months among patients attending Obstetrics and Gynecology department of Adichunchanagiri hospital selected based on convenience sampling procedure. Maternal ABO Blood group of the subjects were determined by Haemagglutination technique.Relationship between maternal ABO Blood group and Pregnancy complications (PE, PIH.GDM) was estimated by calculating odds ratio from logistic regression models using Blood Group O as a reference group and p – value of < 0.05 was considered as statistically significant. The results of the present study have found that maternal AB blood group was highest among preeclampsia and PIH category of cases.The present study conducted have found maternal AB blood group was highest among PIH and preeclampsia category of casesFrom the study conducted we want to conclude non-O blood group had the highest risk compared to O Blood group among pregnancy complications.