美国弗吉尼亚州和潮水地区头晕患者的延迟诊断情况

Kendra N Walker, Kevin M. Guy, Peter G. Volsky
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引用次数: 0

摘要

在一个拥有约 170 万人口的地区(弗吉尼亚州沿海潮水区),确定头晕患者的二次诊断。 这项利用 TriNetX 进行的横断面研究纳入了相关地区在 2010 年至 2020 年期间被诊断为头晕的患者。对同一受试者随后诊断出的前庭疾病或可能与头晕有关的病症进行了编目。 在研究期间,31,670 名受试者被诊断出头晕这一症状;18,390 名受试者随后被诊断出头晕相关的非前庭疾病,930 名受试者随后被诊断出前庭疾病。在确诊头晕后被诊断为前庭疾病的受试者比例(3%)远远低于普通人群的预期标准(25%-34%)。延后诊断出迷宫功能障碍(几率比 [OR],4.8;P < 0.0001)、上半规管开裂(OR,3.1;P = 0.0023)、耳石症(OR,3.1;P = 0.0023)等疾病的比例较高,而延后诊断出良性阵发性位置性眩晕的比例较低(OR,0.56;P < 0.0001)。 本地区预期发病率与观察到的发病率之间的差异表明,前庭疾病很可能被漏诊。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Delayed Diagnoses in Patients With Dizziness in the US Commonwealth of Virginia and the Tidewater Region
In a region of approximately 1.7 million people (Tidewater, coastal Virginia), identify secondary diagnoses in persons with dizziness. This cross-sectional study utilizing TriNetX included individuals in the region of interest diagnosed with dizziness between 2010 and 2020. Subsequent diagnoses of vestibular disease or medical conditions possibly associated with dizziness in the same subjects were catalogued. During the study period, 31,670 subjects were identified with diagnoses of dizziness as a symptom; 18,390 subjects were subsequently given a dizziness-related nonvestibular diagnosis, and 930 were given a subsequent vestibular disease diagnosis. The proportion of subjects diagnosed with vestibular disease (3%) after the dizziness diagnosis is far below expected norms (25%–34%) in the general population. There were greater proportions of delayed diagnoses of labyrinth dysfunction (odds ratio [OR], 4.8; P < 0.0001), superior semicircular canal dehiscence (OR, 3.1; P = 0.0023), otolith disease (OR, 3.1; P = 0.0023), among others, and a decreased proportion of delayed diagnosis of benign paroxysmal positional vertigo (OR, 0.56; P < 0.0001). The discrepancy between expected and observed prevalence in our region indicates that vestibular disease is likely underdiagnosed.
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