SDF 和 AgF 从受感染的牙本质向未受影响的牙齿结构渗透

Riaan Mulder, N. Potgieter, N. Noordien
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摘要

利用扫描电子显微镜-电子显微镜线扫描分析来评估牙科材料中的离子向牙齿结构的移动情况以及离子移动的概念已经非常成熟。本研究旨在比较用二胺氟化银(SDF)和水基氟化银(AgF)处理过的基磨牙的元素分析,并分析 SDF 和 AgF 从感染牙本质向健康牙本质的渗透情况。牙根上的碎屑和污染物被清理干净,并保存至使用前。共有 15 颗初级磨牙有较大的活动性龋损,未延伸至牙髓(标本),被分为三个试验组:二胺氟化银(SDF)(n = 5)、水基氟化银(AgF)(n = 5)和去离子水(W)(n = 5)作为对照组。对牙齿进行切片、包埋和 SEM-EDS 线扫描。线扫描的总长度为 82.65 μm。选择感染牙本质的可见端和受影响较大的牙本质的起点作为起点,以确保感染龋向受影响牙本质过渡区的线分布尽可能标准化。因此,扫描的感染牙本质长度为 22.80 μm(8 个扫描点,每点相距 2.85 μm),包括健康牙本质在内的受影响牙本质长度为 59.8 μm(21 个扫描点)。每个样本的 SEM-EDS 线扫描确定了该样本的氟化物、碘化物和银的平均重量百分比。Kruskall-Wallis 检验和 Tukey's HSD 检验的结果均为 p <0.05。就重量百分比而言,SDF 和 AgF 没有出现明显的氟离子移动。不过,与使用去离子水处理的对照样本相比,使用 SDF 和 AgF 的感染龋齿向健康牙本质的氟迁移量明显增加(p = 0.0010053)。SDF和AgF在碘化物(p = 0.5953)和银(p = 0.3708)从感染性龋齿向健康牙本质移动方面没有明显差异。SDF 和 AgF 在受感染牙本质和受影响/健康牙本质中的离子移动没有明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Penetration of SDF and AgF from the infected dentine towards the unaffected tooth structure
The use of SEM-EDS line scan analysis to evaluate the movement of ions from dental materials towards the tooth structure and the concept of ion movement is well established. This analysis technique was used to determine the ion movement of two commercially available silver- and fluoride-containing products.This study aimed to compare the elemental analysis of primary molar teeth treated with silver diamine fluoride (SDF) and water-based silver fluoride (AgF) and to analyse the penetration of SDF and AgF from the infected dentine towards the healthy dentine. The teeth were cleaned from debris and contaminants off the roots and stored until use. A total of 15 primary molars with large active cavitated lesions, not extending into the pulp (specimens), were divided into three test groups: silver diamine fluoride (SDF) (n = 5), water-based silver fluoride (AgF) (n = 5), and deionised water (W) (n = 5) as the control group. The teeth were sectioned, embedded, and received SEM-EDS line scans. The line scan had a total length of 82.65 μm. The visible end of the infected dentine and the start of the more affected dentine were chosen as the starting point to ensure that the infected caries' line distribution towards the affected dentine's transition area was as standardized as possible. Therefore, the infected dentine length of the scan was 22.80 μm (8 scan points of 2.85 μm apart), and the affected dentine, including the healthy dentine, was 59.8 μm (21 scan points). The SEM-EDS line scan from each specimen determined the average fluoride, iodide, and silver weight percentage for that specimen.The 15 sample SEM-EDS line scans were used to determine the average ion movement in wt%. The Kruskall–Wallis test and Tukey's HSD test were completed at a p < 0.05. SDF and AgF presented no significant fluoride movement in terms of the weight percentage. There was, however, significantly more fluoride movement from infected caries to the healthy dentine with SDF and AgF (p = 0.0010053) compared to the control specimens treated with deionised water. There was no significant difference between SDF and AgF for the movement of the iodide (p = 0.5953) and silver (p = 0.3708) from infected caries to the healthy dentine.SDF and AgF easily penetrated through infected caries and affected tooth structure to the healthy dentine for the line scan of 82.65 μm. There was no significant difference between SDF and AgF for the movement of ions within the infected dentine nor in the affected/healthy dentine.
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