{"title":"细胞中氧化磷酸化和 ATP 合成数学模型的不稳定性和不变量测量","authors":"V. Grytsay","doi":"10.15407/ubj95.06.105","DOIUrl":null,"url":null,"abstract":"The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined. The invariant measure of the strange attractor was calculated, and histograms of its projections on the phase plane were plotted. Some recommendations were made on how to eliminate biochemically the chaotic mode and restore the stability of the self-organization of the cell biosystem. Keywords: ATP, Feigenbaum scenario, invariant measure, Krebs cycle, mathematical model, oxidative phosphorylation, self-organization, strange attractor","PeriodicalId":23007,"journal":{"name":"The Ukrainian Biochemical Journal","volume":"24 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Instability and invariant measure in the mathematical model for oxidative phosphorylation and ATP synthesis in the cell\",\"authors\":\"V. Grytsay\",\"doi\":\"10.15407/ubj95.06.105\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined. The invariant measure of the strange attractor was calculated, and histograms of its projections on the phase plane were plotted. Some recommendations were made on how to eliminate biochemically the chaotic mode and restore the stability of the self-organization of the cell biosystem. Keywords: ATP, Feigenbaum scenario, invariant measure, Krebs cycle, mathematical model, oxidative phosphorylation, self-organization, strange attractor\",\"PeriodicalId\":23007,\"journal\":{\"name\":\"The Ukrainian Biochemical Journal\",\"volume\":\"24 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Ukrainian Biochemical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15407/ubj95.06.105\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Ukrainian Biochemical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15407/ubj95.06.105","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
这项工作的目的是利用数学模型分析细胞中氧化磷酸化和 ATP 合成的过程。根据 ATP 的耗散值,确定了自周期和混沌模式的发生情况。计算了奇异吸引子的不变量,并绘制了其在相平面上的投影直方图。就如何从生化角度消除混沌模式并恢复细胞生物系统自组织的稳定性提出了一些建议。关键词ATP、费根鲍姆情景、不变量、克雷布斯循环、数学模型、氧化磷酸化、自组织、奇异吸引子
Instability and invariant measure in the mathematical model for oxidative phosphorylation and ATP synthesis in the cell
The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined. The invariant measure of the strange attractor was calculated, and histograms of its projections on the phase plane were plotted. Some recommendations were made on how to eliminate biochemically the chaotic mode and restore the stability of the self-organization of the cell biosystem. Keywords: ATP, Feigenbaum scenario, invariant measure, Krebs cycle, mathematical model, oxidative phosphorylation, self-organization, strange attractor