{"title":"COVID-19 SIR 型模型的二维分岔及其流行病学意义的数值研究","authors":"Livia Owen, Jonathan Hoseana, Benny Yong","doi":"10.5614/cbms.2023.6.2.6","DOIUrl":null,"url":null,"abstract":"We study the codimension-two bifurcations exhibited by a recently-developed SIR-type mathematical model for the spread of COVID-19, as its two main parameters —the susceptible individuals’ cautiousness level and the hospitals’ bed-occupancy rate— vary over their domains. We use AUTO to generate the model’s bifurcation diagrams near the relevant bifurcation points: two Bogdanov-Takens points and two generalised Hopf points, as well as a number of phase portraits describing the model’s orbital behaviours for various pairs of parameter values near each bifurcation point. The analysis shows that, when a backward bifurcation occurs at the basic reproduction threshold, the transition of the model’s asymptotic behaviour from endemic to disease-free takes place via an unexpectedly complex sequence of topological changes, involving the births and disappearances of not only equilibria but also limit cycles and homoclinic orbits. Epidemiologically, the analysis confirms the importance of a proper control of the values of the aforementioned parameters for a successful eradication of COVID-19. We recommend a number of strategies by which such a control may be achieved.","PeriodicalId":33129,"journal":{"name":"Communication in Biomathematical Sciences","volume":" 48","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Numerical Study of Codimension-Two Bifurcations of an SIR-Type Model for COVID-19 and Their Epidemiological Implications\",\"authors\":\"Livia Owen, Jonathan Hoseana, Benny Yong\",\"doi\":\"10.5614/cbms.2023.6.2.6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We study the codimension-two bifurcations exhibited by a recently-developed SIR-type mathematical model for the spread of COVID-19, as its two main parameters —the susceptible individuals’ cautiousness level and the hospitals’ bed-occupancy rate— vary over their domains. We use AUTO to generate the model’s bifurcation diagrams near the relevant bifurcation points: two Bogdanov-Takens points and two generalised Hopf points, as well as a number of phase portraits describing the model’s orbital behaviours for various pairs of parameter values near each bifurcation point. The analysis shows that, when a backward bifurcation occurs at the basic reproduction threshold, the transition of the model’s asymptotic behaviour from endemic to disease-free takes place via an unexpectedly complex sequence of topological changes, involving the births and disappearances of not only equilibria but also limit cycles and homoclinic orbits. Epidemiologically, the analysis confirms the importance of a proper control of the values of the aforementioned parameters for a successful eradication of COVID-19. We recommend a number of strategies by which such a control may be achieved.\",\"PeriodicalId\":33129,\"journal\":{\"name\":\"Communication in Biomathematical Sciences\",\"volume\":\" 48\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Communication in Biomathematical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5614/cbms.2023.6.2.6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Communication in Biomathematical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5614/cbms.2023.6.2.6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Mathematics","Score":null,"Total":0}
引用次数: 0
摘要
我们研究了最近开发的 COVID-19 传播 SIR 型数学模型在其两个主要参数--易感个体的谨慎程度和医院的病床占用率--随其域变化时所表现出的二维分岔。我们使用 AUTO 生成了模型在相关分岔点附近的分岔图:两个波格丹诺夫-塔肯斯点和两个广义霍普夫点,以及描述模型在每个分岔点附近不同参数值对的轨道行为的若干相位图。分析表明,当基本繁殖阈值出现向后分叉时,模型的渐近行为从地方病到无病的过渡是通过一连串出乎意料的复杂拓扑变化实现的,其中不仅涉及平衡点的产生和消失,还涉及极限循环和同线性轨道的产生和消失。从流行病学角度看,分析证实了适当控制上述参数值对于成功根除 COVID-19 的重要性。我们推荐了一些可以实现这种控制的策略。
A Numerical Study of Codimension-Two Bifurcations of an SIR-Type Model for COVID-19 and Their Epidemiological Implications
We study the codimension-two bifurcations exhibited by a recently-developed SIR-type mathematical model for the spread of COVID-19, as its two main parameters —the susceptible individuals’ cautiousness level and the hospitals’ bed-occupancy rate— vary over their domains. We use AUTO to generate the model’s bifurcation diagrams near the relevant bifurcation points: two Bogdanov-Takens points and two generalised Hopf points, as well as a number of phase portraits describing the model’s orbital behaviours for various pairs of parameter values near each bifurcation point. The analysis shows that, when a backward bifurcation occurs at the basic reproduction threshold, the transition of the model’s asymptotic behaviour from endemic to disease-free takes place via an unexpectedly complex sequence of topological changes, involving the births and disappearances of not only equilibria but also limit cycles and homoclinic orbits. Epidemiologically, the analysis confirms the importance of a proper control of the values of the aforementioned parameters for a successful eradication of COVID-19. We recommend a number of strategies by which such a control may be achieved.