Rudy Hidayat, Sumariyono, RM Suryo, Anggoro Kusumo Wibowo, A. Ariane, Faisal Parlindungan, Johanda Damanik, A. P. Araminta, Article Info
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Methods: This cross-sectional study is conducted by collecting demographic and clinical data, as well as interviewing adult patients that have been diagnosed with RA at the Rheumatology Clinic of RSCM and have been on disease-modifying antirheumatic drugs (DMARD) treatment for a minimum of 6 months.Results: A total of 94 patients were included in this study. Subjects were predominantly female (93.6%) and had no formal jobs (64.9%). A majority of RA patients exhibited moderate disease activity (48.9%, based on Disease Activity Score-28 with erythrocyte sedimentation rate [DAS-28 ESR]), with a relatively high level of steroid use (86.2%). Notably, most patients started DMARD treatment more than 2 years after the onset of symptoms (45.7%). The proportion of patients achieving therapy target (remission to low disease activity) was 41.5%, with 13.8% attaining remission. Furthermore, Health Assessment Quality (HAQ) scores were found to be significantly lower among the target-achieving group, indicating better quality of life.Conclusion: Therapy target was achieved in 41.5% of RA patients in RSCM, with 13.8% achieving remission. Further research can be conducted to evaluate factors which may affect treatment response among RA patients.","PeriodicalId":32894,"journal":{"name":"Indonesian Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Characteristics and Treatment Responses of Rheumatoid Arthritis Patients at Dr. Cipto Mangunkusumo National General Hospital\",\"authors\":\"Rudy Hidayat, Sumariyono, RM Suryo, Anggoro Kusumo Wibowo, A. Ariane, Faisal Parlindungan, Johanda Damanik, A. P. Araminta, Article Info\",\"doi\":\"10.37275/ijr.v15i2.252\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Rheumatoid arthritis (RA) is a chronic progressive autoimmune rheumatic disease that primarily affects the joints. The goal of RA treatment is to achieve remission or low disease activity, using a treat-to-target approach. This study aims to explore the characteristics of RA patients and evaluate their treatment responses in Dr. Cipto Mangunkusumo National General Hospital (RSCM). Methods: This cross-sectional study is conducted by collecting demographic and clinical data, as well as interviewing adult patients that have been diagnosed with RA at the Rheumatology Clinic of RSCM and have been on disease-modifying antirheumatic drugs (DMARD) treatment for a minimum of 6 months.Results: A total of 94 patients were included in this study. Subjects were predominantly female (93.6%) and had no formal jobs (64.9%). A majority of RA patients exhibited moderate disease activity (48.9%, based on Disease Activity Score-28 with erythrocyte sedimentation rate [DAS-28 ESR]), with a relatively high level of steroid use (86.2%). Notably, most patients started DMARD treatment more than 2 years after the onset of symptoms (45.7%). The proportion of patients achieving therapy target (remission to low disease activity) was 41.5%, with 13.8% attaining remission. Furthermore, Health Assessment Quality (HAQ) scores were found to be significantly lower among the target-achieving group, indicating better quality of life.Conclusion: Therapy target was achieved in 41.5% of RA patients in RSCM, with 13.8% achieving remission. 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引用次数: 0
摘要
导言:类风湿性关节炎(RA)是一种主要影响关节的慢性进行性自身免疫性风湿病。类风湿性关节炎的治疗目标是采用靶向治疗方法,使病情得到缓解或降低疾病活动度。本研究旨在探究西皮托-曼昆库苏莫博士国立综合医院(RSCM)的 RA 患者的特征,并评估他们的治疗反应。研究方法这项横断面研究收集了人口统计学和临床数据,并对在RSCM风湿病诊所确诊为RA且接受改变病情抗风湿药(DMARD)治疗至少6个月的成年患者进行了访谈:本研究共纳入 94 名患者。研究对象主要为女性(93.6%),没有正式工作(64.9%)。大多数 RA 患者表现出中度疾病活动度(48.9%,根据疾病活动度评分-28 和红细胞沉降率[DAS-28 ESR]),使用类固醇的比例相对较高(86.2%)。值得注意的是,大多数患者在症状出现 2 年多后才开始 DMARD 治疗(45.7%)。达到治疗目标(疾病活动缓解至低活动)的患者比例为41.5%,其中13.8%达到缓解。此外,达到治疗目标组的健康评估质量(HAQ)评分明显较低,这表明他们的生活质量更高:结论:RSCM 中 41.5% 的 RA 患者达到了治疗目标,其中 13.8% 的患者病情得到缓解。可开展进一步研究,评估可能影响 RA 患者治疗反应的因素。
Characteristics and Treatment Responses of Rheumatoid Arthritis Patients at Dr. Cipto Mangunkusumo National General Hospital
Introduction: Rheumatoid arthritis (RA) is a chronic progressive autoimmune rheumatic disease that primarily affects the joints. The goal of RA treatment is to achieve remission or low disease activity, using a treat-to-target approach. This study aims to explore the characteristics of RA patients and evaluate their treatment responses in Dr. Cipto Mangunkusumo National General Hospital (RSCM). Methods: This cross-sectional study is conducted by collecting demographic and clinical data, as well as interviewing adult patients that have been diagnosed with RA at the Rheumatology Clinic of RSCM and have been on disease-modifying antirheumatic drugs (DMARD) treatment for a minimum of 6 months.Results: A total of 94 patients were included in this study. Subjects were predominantly female (93.6%) and had no formal jobs (64.9%). A majority of RA patients exhibited moderate disease activity (48.9%, based on Disease Activity Score-28 with erythrocyte sedimentation rate [DAS-28 ESR]), with a relatively high level of steroid use (86.2%). Notably, most patients started DMARD treatment more than 2 years after the onset of symptoms (45.7%). The proportion of patients achieving therapy target (remission to low disease activity) was 41.5%, with 13.8% attaining remission. Furthermore, Health Assessment Quality (HAQ) scores were found to be significantly lower among the target-achieving group, indicating better quality of life.Conclusion: Therapy target was achieved in 41.5% of RA patients in RSCM, with 13.8% achieving remission. Further research can be conducted to evaluate factors which may affect treatment response among RA patients.