用于造口重建的细胞流动真皮基质:一种安全有效的微创技术。

IF 1 4区 医学 Q4 DERMATOLOGY
Carlos Delgado-Miguel, Miriam Miguel-Ferrero, Mercedes Díaz, Juan Camps, Juan Carlos López-Gutiérrez
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引用次数: 0

摘要

背景:目的:描述使用可流动细胞真皮基质(AFDM)对一名有复杂腹壁缺损的儿童患者进行造口重建的情况:病例报告:一名 14 岁女性患者在 6 个月大时被诊断出患有非特异性出血性结肠炎,并接受过多次腹部手术(包括全结肠切除术和末端回肠造口术),她报告称,由于多处腹部疤痕导致多处造口周围皮肤回缩,造口周围皮肤经常出现严重溃疡,继发于不适当的装配和造口袋渗漏。在镇静状态下,做了 2 个小型(5 毫米)肛门周围皮肤切口,通过这些切口剥离并释放真皮瘢痕组织。随后,皮下注射 40 毫升 AFDM,直至造口周围形成均匀、平整的表面。术后数小时,患者在确认造口袋合适且无渗漏后出院。在 18 个月的随访中,患者对手术效果非常满意,造口袋更换次数减少,生活质量提高:本病例报告表明,AFDM 是一种安全有效的造口重建微创技术,并发症极少,中期效果令人满意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acellular flowable dermal matrix for ostomy reconstruction: a safe and effective minimally invasive technique.

Background: Acellular dermal matrices have long been used for complex abdominal wall closure and, more recently, for ostomy reconstruction.

Purpose: To describe ostomy reconstruction with acellular flowable dermal matrix (AFDM) in a pediatric patient with a complex abdominal wall defect.

Case report: A 14-year-old female who was diagnosed with unspecific hemorrhagic colitis at age 6 months and who underwent several abdominal surgeries (including total colectomy and terminal ileostomy) reported frequent, severe periostomy skin ulcerations secondary to improper fitting and ostomy bag leakage due to multiple periostomy skin retraction as a result of multiple abdominal scars. Under sedation, 2 small (5 mm) peristomal skin incisions were made, through which dissection and release of dermal scar tissue was performed. Afterwards, AFDM 40 mL was injected subcutaneously until a uniform, flat surface around the ostomy was achieved. The patient was discharged a few hours postoperatively, after verification of proper fit of the ostomy bag with no leakage. At 18-month follow-up, the patient was very satisfied with the result, with fewer ostomy bag changes and improved quality of life.

Conclusion: This case report indicates that AFDM is a safe and effective minimally invasive technique for ostomy reconstruction, with minimal complications and satisfactory medium-term results.

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来源期刊
Wound management & prevention
Wound management & prevention Nursing-Medical and Surgical Nursing
CiteScore
1.70
自引率
8.30%
发文量
41
期刊介绍: Information not localized
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