Tao Ding, Yi Zhu, Zhong-Man Zhang, Yue Zou, Di An, Wei Li, Xu-Feng Chen
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引用次数: 0
摘要
Kodamaea ohmeri(K. ohmeri)是一种腹孢子源性酵母菌,属于腹孢子源属和酵母科。最近发现它可引起各种类型的感染,尤其是在免疫力低下的重症患者中。本研究描述了一例在静脉-动脉体外膜氧合过程中由 K. ohmeri 引起的医院获得性肺炎。体外膜肺氧合(ECMO)是一种辅助医疗技术,可为患者提供临时心肺支持。以往的观察表明,在使用 ECMO 期间,患者的免疫功能通常会下降,从而使感染成为 ECMO 的主要并发症之一。K. ohmeri 是一种罕见的致病真菌,尤其是在使用血管导管的免疫功能低下患者中,而两性霉素 B 是治疗 K. ohmeri 感染最常用的抗真菌疗法。提高人们对罕见真菌感染的认识并积极治疗非常重要。
Hospital‑acquired pneumonia caused by Kodamaea ohmeri during extracorporeal membrane oxygenation treatment: A case report and literature review.
Kodamaea ohmeri (K. ohmeri) is an ascosporogenic species of yeast that belongs to the genus Ascosporogenous and the family of Saccharomycetaceae. It has recently been found to cause various types of infections, particularly in critically ill immunocompromised patients. The present study describes a case of hospital-acquired pneumonia caused by K. ohmeri during veno-arterial extracorporeal membrane oxygenation. The fungal culture turned negative after the administration of caspofungin and amphotericin B. Extracorporeal membrane oxygenation (ECMO) is an adjunctive medical technique that provides temporary cardiopulmonary support for patients. Previous observations have suggested that the immune function of patients will typically decline during the use of ECMO, rendering infection to be one of the main complications of ECMO. K. ohmeri is a rare pathogenic fungus, particularly in immunocompromised individuals with vascular catheters, while amphotericin B is the most common antifungal therapy administered to treat K. ohmeri infections. It is important to raise awareness of rare fungal infections and actively treat them.