Eren Yılmaz, Serbülent Türk, Alican Bahadır Semerci, Mine Kırkbınar, Erhan İbrahimoğlu, Fatih Çalışkan
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引用次数: 0
摘要
金属钛（Ti）植入物表面的生物特性和抗菌性能需要改进。为此，在钛板表面成功开发了一种新型掺硼生物活性磷灰石-硅灰石（AW）涂层。研究了添加硼元素对 AW 涂层的微观结构、机械性能和生物特性的影响。随着硼（B）的加入，AW 涂层的形态变得疏松而紧密。在生物特性方面，磷灰石的形成率随着硼的添加而增加，细胞存活率从大约 66% 增加到 81%。硼的添加使 AW 涂层的弹性模量从 24-46 GPa 增加，硬度增加了约 2.5 倍。此外，虽然在 AW 涂层中没有观察到抗菌活性，但硼的添加略微引入了抗菌特性。所获得的新型 AW/B 复合涂层有望用于钛种植体表面。
Bioactive apatite–wollastonite glass ceramics coating on metallic titanium for biomedical applications: effect of boron
Metallic titanium (Ti) implant surfaces need improvement for bioproperties and antibacterial behavior. For this purpose, a new boron-doped bioactive apatite–wollastonite (AW) coating was successfully developed on the Ti plate surface. The effects of boron addition on the microstructure, mechanical properties, and bioproperties of the AW coating were investigated. With the addition of boron (B), the AW coating morphology became less porous and compact. In terms of bio properties, the rate of apatite formation increased with the addition of B, and the cell viability rate increased from approximately 66–81%. B addition increased the elastic modulus of the AW coating from about 24–46 GPa and increased its hardness about 2.5 times. In addition, while no antibacterial activity was observed in the AW coating, the addition of boron slightly introduced antibacterial properties. The novel AW/B composite coating obtained is promising for Ti implant surfaces.
期刊介绍：
Biological inorganic chemistry is a growing field of science that embraces the principles of biology and inorganic chemistry and impacts other fields ranging from medicine to the environment. JBIC (Journal of Biological Inorganic Chemistry) seeks to promote this field internationally. The Journal is primarily concerned with advances in understanding the role of metal ions within a biological matrix—be it a protein, DNA/RNA, or a cell, as well as appropriate model studies. Manuscripts describing high-quality original research on the above topics in English are invited for submission to this Journal. The Journal publishes original articles, minireviews, and commentaries on debated issues.
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