下消化道出血患者接受下消化道内窥镜检查的临床结果:三级中心的研究结果

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-03-01 Epub Date: 2023-12-15 DOI:10.4103/sjg.sjg_316_23
Noura S Alhassan, Mansour A Altwuaijri, Sulaiman A Alshammari, Khaled M Alshehri, Yazeed A Alkhayyal, Fahad A Alfaiz, Mohammad O Alomar, Saad S Alkhowaiter, Nuha Y Al Amaar, Thamer A Bin Traiki, Khayal A Al Khayal
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引用次数: 0

摘要

背景:下消化道出血(LGIB)是一种急症,发病率越来越高,而且仍然是住院治疗的常见原因。临床结果可能因多种因素而异,包括出血原因、严重程度和治疗策略的有效性。本研究旨在全面报告接受下腔内镜检查的 LGIB 患者的临床结果:方法:纳入2015年5月至2021年12月期间因直肠周围新鲜出血而接受急诊下端内窥镜检查的所有患者。主要结果是确定初步控制出血后的再出血率。其次是测量临床结果以及导致干预和再入院的潜在预测因素:共纳入 84 名患者。内镜检查时发现有活动性出血的患者占 20%。90天内再次出血的患者占总人数的6%,其中2例(2.38%)发生在同一次入院。19%的病例在90天内再次入院。在所有病例中,32.5%的患者接受了上消化道内窥镜检查,结果发现上消化道内窥镜检查是干预的重要预测因素(OR 4.1,P = 0.013)。个人炎症性肠病(IBD)病史和初次使用乙状结肠镜检查是再次入院的重要预测因素[(OR 5.09,P = 0.008)和(OR 5.08,P = 0.019)]:LGIB是一种急症,必须通过所有相关服务部门之间达成的协议进行识别和管理,以确定哪些患者需要在12小时内进行上消化道内镜检查、入住ICU或急诊内镜检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical outcomes of lower gastrointestinal bleeding in patients managed with lower endoscopy: A tertiary center results.

Background: Lower gastrointestinal bleeding (LGIB) is an urgent presentation with increasing prevalence and remains a common cause of hospitalization. The clinical outcome can vary based on several factors, including the cause of bleeding, its severity, and the effectiveness of management strategies. The aim of this study is to provide a comprehensive report on the clinical outcomes observed in patients with LGIB who underwent lower endoscopy.

Methods: All patients who underwent emergency lower endoscopy for fresh bleeding per rectum, from May 2015 to December 2021, were included. The primary outcome was to identify the rate of rebleeding after initial control of bleeding. The second was to measure the clinical outcomes and the potential predictors leading to intervention and readmission.

Results: A total of 84 patients were included. Active bleeding was found in 20% at the time of endoscopy. Rebleeding within 90 days occurred in 6% of the total patients; two of which (2.38%) were within the same admission. Ninety-day readmission was reported in 19% of the cases. Upper endoscopy was performed in 32.5% of the total cases and was found to be a significant predictor for intervention (OR 4.1, P = 0.013). Personal history of inflammatory bowel disease (IBD) and initial use of sigmoidoscopy were found to be significant predictors of readmission [(OR 5.09, P = 0.008) and (OR 5.08, P = 0.019)].

Conclusions: LGIB is an emergency that must be identified and managed using an agreed protocol between all associated services to determine who needs upper GI endoscopy, ICU admission, or emergency endoscopy within 12 hours.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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