多次潜水后静脉气体栓塞(VGE)在潜水员内部的变化。

IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
David J Doolette, F Gregory Murphy
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引用次数: 0

摘要

简介:在减压程序研究中,静脉气体栓塞(VGE)被广泛用作减压病(DCS)的替代终点。重复相同的潜水后,潜水后 VGE 等级的峰值差异很大,但对于 VGE 等级的差异在潜水员之间和潜水员内部所占的比例却知之甚少:在受控实验室条件下,对 834 人次的六种潜水情况进行了回顾性分析,并测量了潜水后的 VGE 值。在这些数据中,有 151 名潜水员在同一剖面上进行了 2 至 9 次重复潜水,每次间隔至少一周(共计 693 人次)。采用以潜水员为随机变量的混合效应模型和相关的类内相关系数,分析了潜水员之间和潜水员内部在潜水后 VGE 等级峰值方面的差异:结果:大多数潜水员在同一剖面上重复潜水后产生的 VGE 等级差异很大。类内相关系数(可重复性)为 0.33,表明 VGE 等级中 33% 的变化是潜水员之间的变化;相应地,VGE 等级中 67% 的变化是潜水员内部的变化。DCS 病例与个体潜水员的最高 VGE 等级有关,而与较低的 VGE 等级无关:这些数据表明,在同一潜水剖面上重复潜水后,潜水员内部的 VGE 等级变化很大,并表明潜水员内部对 DCS 的易感性存在很大差异。潜水后 VGE 等级对于评估个体潜水员的减压实践并无用处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Within-diver variability in venous gas emboli (VGE) following repeated dives.

Introduction: Venous gas emboli (VGE) are widely used as a surrogate endpoint instead of decompression sickness (DCS) in studies of decompression procedures. Peak post-dive VGE grades vary widely following repeated identical dives but little is known about how much of the variability in VGE grades is proportioned between-diver and within-diver.

Methods: A retrospective analysis of 834 man-dives on six dive profiles with post-dive VGE measurements was conducted under controlled laboratory conditions. Among these data, 151 divers did repeated dives on the same profile on two to nine occasions separated by at least one week (total of 693 man-dives). Data were analysed for between- and within-diver variability in peak post-dive VGE grades using mixed-effect models with diver as the random variable and associated intraclass correlation coefficients.

Results: Most divers produced a wide range of VGE grades after repeated dives on the same profile. The intraclass correlation coefficient (repeatability) was 0.33 indicating that 33% of the variability in VGE grades is between-diver variability; correspondingly, 67% of variability in VGE grades is within-diver variability. DCS cases were associated with an individual diver's highest VGE grades and not with their lower VGE grades.

Conclusions: These data demonstrate large within-diver variability in VGE grades following repeated dives on the same dive profile and suggest there is substantial within-diver variability in susceptibility to DCS. Post-dive VGE grades are not useful for evaluating decompression practice for individual divers.

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来源期刊
Diving and hyperbaric medicine
Diving and hyperbaric medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
1.70
自引率
22.20%
发文量
37
审稿时长
>12 weeks
期刊介绍: Diving and Hyperbaric Medicine (DHM) is the combined journal of the South Pacific Underwater Medicine Society (SPUMS) and the European Underwater and Baromedical Society (EUBS). It seeks to publish papers of high quality on all aspects of diving and hyperbaric medicine of interest to diving medical professionals, physicians of all specialties, scientists, members of the diving and hyperbaric industries, and divers. Manuscripts must be offered exclusively to Diving and Hyperbaric Medicine, unless clearly authenticated copyright exemption accompaniesthe manuscript. All manuscripts will be subject to peer review. Accepted contributions will also be subject to editing.
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