Analysis of Antioxidant Property from Water Extraction of Garcia Mangostana Using Response Surface Methodology

Mangosteen (Garcia mangostana) is an exotic fruit that can be found widely in Southeast Asia. Mangosteen pericarp contains bioactive compound that has pharmacological properties, including antioxidants, anticarcinogenic, and also suggested its applicability for skincare products. Water extraction is more applicable for industry due to simple process, low cost, and neutral reaction. In this study, water extraction on the pericarp of mangosteen was applied and the operating parameters were discussed by using Response Surface Methodology (RSM) for high recovery of antioxidant extract from the mangosteen pericarp. The experimental design used three factors, solid-to-liquid ratio (g/ml), temperature (oC) and extraction time (hour), were analyzed to discuss two responses, DPPH radical scavenging effect (DPPH) and Ferric Reducing Antioxidant Power (FRAP). Under the operating conditions, the highest FRAP is 0.818 abs at the factors of 1:10 (g/ml), 65 oC, and 3-hour. DPPH is significantly high for all RSM pattern. The optimum parameters determined by using RSM are at 1:10 (g/ml), 59.74 oC, and 2.87 hours with DPPH 81.01% and FRAP 0.789 abs.