儿童术后残余左向右分流病变术后即刻经导管设备闭合术

M. Kidwai, S. Abqari, Mohammad Mirza Kamran, Mohammad Azam Haseen, Mayank Yadav, Shamayal Rabbani, Md Ghazanfar
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摘要

术后残留分流以室间隔缺损(VSD)和动脉导管未闭(PDA)的形式存在,如果血流动力学显著,可导致左心室容量过载和恢复延迟。标准的治疗方法是重做手术,这可能导致显著的发病率和死亡率。在选定的情况下,这种缺陷的设备闭合提供了另一种管理策略。本研究的目的是检查装置关闭残余的左至右分流在儿科年龄组在术后立即期间的效用。回顾性分析2018年3月至2022年12月住院记录,分析术后残留分流装置关闭情况。分析手术成功率、并发症、住院时间及中期随访情况。术后共4例患者行VSD装置关闭术,1例患者行PDA装置关闭术。经导管手术的中位年龄为6岁(范围3-10岁)。手术和器械关闭之间的中位时间间隔为4天(范围2-15天)。3例患者的适应症是左心室容量超载,2例患者有持续性胸腔积液。Qp: 5例患者的q值均大于1.5:1。4例患者使用amplatzer导管闭塞器I (ADO-I), 1例患者使用ADO-II。部署后没有残留的分流器,没有主要并发症。平均随访时间2年,所有患者均无残留分流管。本病例系列仅局限于5例,表明装置关闭术后显著血流动力学残留的左至右分流病变是大龄儿童重做手术的有效替代策略。进一步的研究需要更大的样本量,需要更长的随访时间来评估其长期的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transcatheter Device Closure of Postsurgical Residual Left to Right Shunt Lesions in Children during the Immediate Postoperative Period
Postoperative residual shunts in the form of ventricular septal defects (VSD) and patent ductus arteriosus (PDA), if hemodynamically significant, can lead to symptoms of left ventricular volume overload and delayed recovery. The standard management is redo surgery, which can lead to significant morbidity and mortality. Device closure of such defects offers an alternative management strategy in selected cases. This study aims to examine the utility of device closure of residual left-to-right shunts in the pediatric age group in the immediate postoperative period. A retrospective analysis of hospital records was done from March 2018 to December 2022 to analyze the device closure in postoperative residual shunts. The success rate, complications, hospital length of stay, and midterm follow-up were analyzed. A total of four postoperative patients underwent VSD device closure and one patient underwent PDA device closure. The median age at transcatheter procedure was 6 years (range 3–10 years). The median time interval between the surgical procedure and the device closure procedure was 4 days (range 2–15 days). The indication for device closure was left ventricular volume overload in three patients and two patients had persistent pleural effusion. Qp:Qs was more than 1.5:1 in all five patients. The amplatzer duct occluder I (ADO-I) device was used in four patients and the ADO-II in one patient. There was no residual shunt post-deployment, with no major complication. The mean follow-up period was 2 years and all the patients had no residual shunt. This case series, with its limitation of only five cases, has shown that device closure of hemodynamically significant residual postoperative left-to-right shunt lesions is an effective alternative strategy to redo surgery in older children. Further study is required with a larger sample size, and a longer follow-up is needed to evaluate its long-term safety and efficacy.
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