{"title":"自发性埃默里病羔羊外周血参数的变化","authors":"O. V. Filipenko","doi":"10.32718/nvlvet11212","DOIUrl":null,"url":null,"abstract":"In order to study the morphological and biochemical parameters of the blood of lambs affected by the causative agent of eimeria, an experimental group of animals of the Romanov breed, two months old, was formed. The lambs were spontaneously infected with the causative agent of eimeria, which was confirmed by laboratory and clinical studies. The second group of animals was free from eimeria and was kept separately. According to the results of blood tests of sick lambs, a decrease in the number of peripheral blood erythrocytes by 29.66 %, an increase in the total number of leukocytes by 47.12 % compared to the blood parameters of the control group of animals was revealed. A change in leukogram parameters was also noted: an increase in the number of eosinophils by 55.43 %, young neutrophils by 75 %. At the same time, there was a decrease in the number of rod-shaped neutrophils and an increase in the number of segmented neutrophils by 8.7 and 29.51 %, respectively. A decrease in the number of lymphocytes and monocytes by 31.68 and 12 %, respectively, was registered. Biochemical changes in the blood serum of sick lambs also underwent changes. A decrease in the content of total protein by 36.06 %, albumin by 13.09 % was established. An increase in the content of globulins and dysproteinemia was noted. Hemoglobin content was also reduced compared to blood parameters of healthy lambs by 32.25 %, as well as glucose content by 27.83 %. The activity level of ALT and AST increased by 43.43 and 33.15 %, respectively, as well as a slight decrease in GGT activity. The difference was statistically significant (Р < 0.01 and Р < 0.05). Differences in the blood parameters of sick lambs have been established and indicate a syndrome of the body's general inflammatory reaction, anemia, damage to the alimentary canal by the causative agent of eimeria and intoxication.","PeriodicalId":21703,"journal":{"name":"Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies","volume":"48 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Changes in peripheral blood parameters of lambs with spontaneous eimeriosis\",\"authors\":\"O. V. Filipenko\",\"doi\":\"10.32718/nvlvet11212\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In order to study the morphological and biochemical parameters of the blood of lambs affected by the causative agent of eimeria, an experimental group of animals of the Romanov breed, two months old, was formed. The lambs were spontaneously infected with the causative agent of eimeria, which was confirmed by laboratory and clinical studies. The second group of animals was free from eimeria and was kept separately. According to the results of blood tests of sick lambs, a decrease in the number of peripheral blood erythrocytes by 29.66 %, an increase in the total number of leukocytes by 47.12 % compared to the blood parameters of the control group of animals was revealed. A change in leukogram parameters was also noted: an increase in the number of eosinophils by 55.43 %, young neutrophils by 75 %. At the same time, there was a decrease in the number of rod-shaped neutrophils and an increase in the number of segmented neutrophils by 8.7 and 29.51 %, respectively. A decrease in the number of lymphocytes and monocytes by 31.68 and 12 %, respectively, was registered. Biochemical changes in the blood serum of sick lambs also underwent changes. A decrease in the content of total protein by 36.06 %, albumin by 13.09 % was established. An increase in the content of globulins and dysproteinemia was noted. Hemoglobin content was also reduced compared to blood parameters of healthy lambs by 32.25 %, as well as glucose content by 27.83 %. The activity level of ALT and AST increased by 43.43 and 33.15 %, respectively, as well as a slight decrease in GGT activity. The difference was statistically significant (Р < 0.01 and Р < 0.05). Differences in the blood parameters of sick lambs have been established and indicate a syndrome of the body's general inflammatory reaction, anemia, damage to the alimentary canal by the causative agent of eimeria and intoxication.\",\"PeriodicalId\":21703,\"journal\":{\"name\":\"Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies\",\"volume\":\"48 5\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32718/nvlvet11212\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32718/nvlvet11212","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
为了研究艾美耳球虫致病菌对羔羊血液形态和生化参数的影响,采用2月龄的罗曼诺夫(Romanov)品种作为实验动物。经实验室和临床研究证实,羔羊自发感染了艾美耳球虫病原体。第二组无艾美耳球虫,单独饲养。根据病羔羊的血液检查结果,与对照组相比,外周血红细胞数量减少了29.66%,白细胞总数增加了47.12%。白细胞参数的变化也被注意到:嗜酸性粒细胞增加了55.43%,年轻中性粒细胞增加了75%。同时,杆状中性粒细胞的数量减少了8.7%,节段性中性粒细胞的数量增加了29.51%。淋巴细胞和单核细胞的数量分别减少了31.68%和12%。病羔羊的血清生化变化也发生了变化。总蛋白含量降低36.06%,白蛋白含量降低13.09%。注意到球蛋白和蛋白异常血症的含量增加。与健康羔羊的血液参数相比,血红蛋白含量降低了32.25%,葡萄糖含量降低了27.83%。谷丙转氨酶和谷草转氨酶活性分别升高43.43%和33.15%,而谷草转氨酶活性略有下降。差异有统计学意义(Р < 0.01, Р < 0.05)。患病羔羊血液参数的差异已经确定,这表明身体的一般炎症反应、贫血、艾美拉球虫病原体对消化道的损害和中毒的综合征。
Changes in peripheral blood parameters of lambs with spontaneous eimeriosis
In order to study the morphological and biochemical parameters of the blood of lambs affected by the causative agent of eimeria, an experimental group of animals of the Romanov breed, two months old, was formed. The lambs were spontaneously infected with the causative agent of eimeria, which was confirmed by laboratory and clinical studies. The second group of animals was free from eimeria and was kept separately. According to the results of blood tests of sick lambs, a decrease in the number of peripheral blood erythrocytes by 29.66 %, an increase in the total number of leukocytes by 47.12 % compared to the blood parameters of the control group of animals was revealed. A change in leukogram parameters was also noted: an increase in the number of eosinophils by 55.43 %, young neutrophils by 75 %. At the same time, there was a decrease in the number of rod-shaped neutrophils and an increase in the number of segmented neutrophils by 8.7 and 29.51 %, respectively. A decrease in the number of lymphocytes and monocytes by 31.68 and 12 %, respectively, was registered. Biochemical changes in the blood serum of sick lambs also underwent changes. A decrease in the content of total protein by 36.06 %, albumin by 13.09 % was established. An increase in the content of globulins and dysproteinemia was noted. Hemoglobin content was also reduced compared to blood parameters of healthy lambs by 32.25 %, as well as glucose content by 27.83 %. The activity level of ALT and AST increased by 43.43 and 33.15 %, respectively, as well as a slight decrease in GGT activity. The difference was statistically significant (Р < 0.01 and Р < 0.05). Differences in the blood parameters of sick lambs have been established and indicate a syndrome of the body's general inflammatory reaction, anemia, damage to the alimentary canal by the causative agent of eimeria and intoxication.