合并症及其对 COVID-19 患者预后的影响

Alaa Hussein Khudhair Al-Janabi
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摘要

背景:相关疾病的存在是COVID-19患者治疗和管理的主要临床挑战。目的:研究常见合并症对新冠肺炎确诊病例严重程度、转归和住院时间的影响。方法:描述性横断面研究。目前的研究涉及2574种情况。2020年3月至9月期间,伊拉克巴比伦省2个新冠肺炎中心的所有PCR确诊病例都被纳入其中。数据收集方法包括社会人口统计数据、感染的临床表现及其严重程度、患者可能患有的相关合并症以及住院时间和结果。结果:研究显示,患者平均年龄为48.7(±16.4)岁,糖尿病是最常见的合并症(25.0%),其次是高血压(23.4%),有合并症的患者(84.0%)有重症/危重症,无合并症患者(54.1%)有重症/危重症,P值为(0.001),有合并症患者的病死率为26.4%,无合并症患者的病死率为10.6% (P<0.001)。结论:相关疾病对COVID-19感染的严重程度、持续时间和转结局有显著影响,有合并症的患者必须采取额外的预防措施,应在一开始就接种COVID-19疫苗,防止病情恶化和不良后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Comorbidities and it Impact on the outcome of COVID-19 Patients
Background: The existence of associated diseases presents a major clinical challenge in the  approach and management of COVID-19 patients. Objectives: To study the effect of common  comorbidities on the severity, outcome, and duration of hospital stay among confirmed COVID 19 cases. Methods: Descriptive cross-sectional study. A 2574 conditions were involved in the  current study. All the PCR confirmed cases in 2 COVID-19 centers at Babylon province/Iraq were  included for the period from March till September 2020. A constructed questionnaire used as a  method of data collection which including socio-demographic data, clinical presentation of the  infection and its severity, associated comorbidities that the patient may suffer from and the duration of hospital stay and outcome. Results: the study shown that the mean of age 48.7 (±16.4)  years, Diabetes Mellitus was the most prevalent associated comorbidity (25.0%), then hypertension with a prevalence of (23.4%), (84.0%) of the patients who had comorbidities had severe/critical illness compared to (54.1%) for patients who are free from comorbid illnesses with  significant P value of (0.001), case-mortality ratio was 26.4% among patients with comorbidities  compared to 10.6% among the patients free from comorbidity (P<0.001). Conclusions: associated  diseases had significant impact on the severity of the duration and outcome of COVID-19  infection, patients with comorbidities must have additional preventive measures and they should  be at the beginning in receiving the COVID-19 vaccine to prevent the deteriorations and bad  consequences. 
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