{"title":"病灶性常发性间质性肺炎是进展性肺纤维化的一个关键预后因素","authors":"Yukio Tsushima, Ethan N. Okoshi, Sousuke Ishijima, Andrey Bychkov, Kris Lami, Shimpei Morimoto, Yasuhiko Yamano, Kensuke Kataoka, Takeshi Johkoh, Yasuhiro Kondoh, Junya Fukuoka","doi":"10.1101/2023.12.07.23298650","DOIUrl":null,"url":null,"abstract":"Progressive pulmonary fibrosis (PPF) is a newly recognized clinical phenotype of interstitial lung diseases in the 2022 interstitial pulmonary fibrosis (IPF) guidelines. This category is based entirely on clinical and radiological factors, and the background histopathology is unknown. Our objective was to investigate the histopathological characteristics of PPF and to examine the correlation between usual interstitial pneumonia (UIP) and prognosis in this new disease type. We hypothesized that the presence of UIP-like fibrosis predicts patients’ survival in PPF cases.","PeriodicalId":501528,"journal":{"name":"medRxiv - Pathology","volume":"7 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Presence Of Focal Usual Interstitial Pneumonia Is A Key Prognostic Factor In Progressive Pulmonary Fibrosis\",\"authors\":\"Yukio Tsushima, Ethan N. Okoshi, Sousuke Ishijima, Andrey Bychkov, Kris Lami, Shimpei Morimoto, Yasuhiko Yamano, Kensuke Kataoka, Takeshi Johkoh, Yasuhiro Kondoh, Junya Fukuoka\",\"doi\":\"10.1101/2023.12.07.23298650\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Progressive pulmonary fibrosis (PPF) is a newly recognized clinical phenotype of interstitial lung diseases in the 2022 interstitial pulmonary fibrosis (IPF) guidelines. This category is based entirely on clinical and radiological factors, and the background histopathology is unknown. Our objective was to investigate the histopathological characteristics of PPF and to examine the correlation between usual interstitial pneumonia (UIP) and prognosis in this new disease type. We hypothesized that the presence of UIP-like fibrosis predicts patients’ survival in PPF cases.\",\"PeriodicalId\":501528,\"journal\":{\"name\":\"medRxiv - Pathology\",\"volume\":\"7 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2023.12.07.23298650\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2023.12.07.23298650","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Presence Of Focal Usual Interstitial Pneumonia Is A Key Prognostic Factor In Progressive Pulmonary Fibrosis
Progressive pulmonary fibrosis (PPF) is a newly recognized clinical phenotype of interstitial lung diseases in the 2022 interstitial pulmonary fibrosis (IPF) guidelines. This category is based entirely on clinical and radiological factors, and the background histopathology is unknown. Our objective was to investigate the histopathological characteristics of PPF and to examine the correlation between usual interstitial pneumonia (UIP) and prognosis in this new disease type. We hypothesized that the presence of UIP-like fibrosis predicts patients’ survival in PPF cases.
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