中低收入国家机械性肠梗阻病因的系统综述方案:过去二十年有什么变化吗?

Yakubu Kevin Kwarshak, Mohammed Nakodi Yisa, Oghenegare Asheaba Kigbu, Daniel Akut John, Karen Chineme Ubabuike, Nankam David Jimwan, Peter Mkurtar Yawe
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引用次数: 0

摘要

背景:尽管机械性肠梗阻的病因多种多样,但似乎因地理位置和年龄的不同而存在很大差异。从地域上看,在高收入国家和中低收入国家,术后粘连和疝气分别是机械性肠梗阻最常见的病因。中低收入国家的这一趋势是否发生了变化是外科界的一个猜测。因此,为了填补这一知识空白,本研究旨在系统地回顾有关机械性肠梗阻病因的现有文献,重点了解中低收入国家儿科和成人中最常见的机械性肠梗阻病因,以指导外科实践:本研究是根据《2015 年系统综述和元分析首选报告项目协议》(PRISMA-P 2015)的指导原则设计和编写的。但是,系统性综述的结果将根据系统性综述和 Meta 分析首选报告项目 (PRISMA) 声明进行报告。我们将考虑 2002 年至 2022 年间以英语和法语发表的、报道中低收入国家任何年龄组机械性肠梗阻病因的研究。我们将使用 Ovid MEDLINE、Ovid Embase、EBSCO 上的 CINAHL 和 Web of Science 数据库进行文献检索,使用相关主题词、关键词和同义词,并使用布尔运算符进行组合,以完善检索结果。将对检索到的文献的参考文献进行人工检索。检索到的文章将导入 Zotero 进行去重。由此产生的一系列标题和摘要将上传到 Rayyan(人工智能辅助在线系统综述工具),并在那里进行双重检查,以确定符合纳入条件的文章。两名独立审稿人将对拟纳入的文章进行筛选,出现分歧时将通过讨论解决,或由第三名审稿人作为决胜者。此外,数据提取将由一位审稿人完成,并由另一位审稿人确认。两位独立审稿人将使用乔安娜-布里格斯研究所(JBI)的工具对纳入研究的质量进行严格评估。我们预计,符合条件的研究在设计、相关结果、人群和并发症等方面将存在很大差异。因此,我们可能会使用图表、图形和表格对结果进行描述性综合,而不会进行荟萃分析。在可能的情况下,我们将使用基于年龄、世界卫生组织地区和大洲的概念框架进行子分析:由于所需的数据已经公开,因此不需要伦理批准。研究结果将在同行评审期刊上发表。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Systematic Review Protocol of aetiology of mechanical bowel obstruction in Low-and-middle income countries: Has anything changed in the last two decades?
Background: Despite various causes of mechanical obstruction, there appears to be a great deal of variation depending on geographical location and age. Geographically, postoperative adhesions and hernia have been documented as the most common aetiology of mechanical bowel obstruction in high-income and low-and-middle-income countries, respectively. Whether there has been a change in this trend in low- and middle-income countries is a matter of speculation in the surgical community. Therefore, to fill this knowledge gap, this study aims to systematically review the existing literature on the aetiology of mechanical bowel obstruction with a focus on understanding the most common cause of mechanical bowel obstruction in low- and middle-income countries in both paediatric and adult populations to guide surgical practice. Methodology and Analysis: This protocol was designed and written according to the guidelines of the Preferred Reporting Items for Systematic Review and Meta-analysis Protocol 2015 (PRISMA-P 2015) statement. However, the results of the systematic review will be reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. We will consider studies published in English and French between 2002 and 2022 that reported on the aetiology of mechanical bowel obstruction in any age group in low- and middle-income countries. We will conduct a literature search using Ovid MEDLINE, Ovid Embase, CINAHL on EBSCO and Web of Science databases employing relevant subject headings, keywords and synonyms, which will be combined using Boolean operators to refine the search results. A hand search of references of retrieved literature will be conducted. The retrieved articles will be imported into Zotero for de-duplication. The resulting set of titles and abstracts will be uploaded to Rayyan (an AI-assisted online systematic review tool), where they will be double-checked to identify articles eligible for inclusion. Two independent reviewers will screen articles to be included and disagreement will be resolved by discussion or by a third reviewer as a tie-breaker. Also, data extraction will be done by one reviewer and confirmed by another. Critical appraisal to assess the quality of the included studies will be carried out by two independent reviewers using the Joanna Briggs Institute (JBI) tools. We anticipate that the eligible studies will be quite heterogeneous in terms of their design, outcomes of interest, populations and comorbidities. Therefore, results may be synthesised descriptively without meta-analysis using charts, graphs and tables. Where possible, we will conduct a sub-analysis using conceptual frameworks based on age, WHO regions and continents. Ethics and Dissemination: No ethical approval will be sought because the required data is already in the public domain. Findings will be published in peer-reviewed journals.
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