{"title":"动力-发动机负载形式的动态绝对集中稳健性","authors":"Badal Joshi, Gheorghe Craciun","doi":"10.1137/22m1535450","DOIUrl":null,"url":null,"abstract":"SIAM Journal on Applied Mathematics, Volume 83, Issue 6, Page 2237-2259, December 2023. <br/> Abstract. In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical network with output robustness and therefore is essential for its functioning in a highly variable environment. It is important to identify the structure of the dynamical system as well as the constraints required for dynamic ACR. We propose a power-engine-load form of dynamic ACR and obtain results regarding convergence to the ACR value based on this form.","PeriodicalId":51149,"journal":{"name":"SIAM Journal on Applied Mathematics","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Power-Engine-Load Form for Dynamic Absolute Concentration Robustness\",\"authors\":\"Badal Joshi, Gheorghe Craciun\",\"doi\":\"10.1137/22m1535450\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"SIAM Journal on Applied Mathematics, Volume 83, Issue 6, Page 2237-2259, December 2023. <br/> Abstract. In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical network with output robustness and therefore is essential for its functioning in a highly variable environment. It is important to identify the structure of the dynamical system as well as the constraints required for dynamic ACR. We propose a power-engine-load form of dynamic ACR and obtain results regarding convergence to the ACR value based on this form.\",\"PeriodicalId\":51149,\"journal\":{\"name\":\"SIAM Journal on Applied Mathematics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2023-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SIAM Journal on Applied Mathematics\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://doi.org/10.1137/22m1535450\",\"RegionNum\":4,\"RegionCategory\":\"数学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATHEMATICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SIAM Journal on Applied Mathematics","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1137/22m1535450","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
Power-Engine-Load Form for Dynamic Absolute Concentration Robustness
SIAM Journal on Applied Mathematics, Volume 83, Issue 6, Page 2237-2259, December 2023. Abstract. In a reaction network, the concentration of a species with the property of dynamic absolute concentration robustness (dynamic ACR) converges to the same value independent of the overall initial values. This property endows a biochemical network with output robustness and therefore is essential for its functioning in a highly variable environment. It is important to identify the structure of the dynamical system as well as the constraints required for dynamic ACR. We propose a power-engine-load form of dynamic ACR and obtain results regarding convergence to the ACR value based on this form.
期刊介绍:
SIAM Journal on Applied Mathematics (SIAP) is an interdisciplinary journal containing research articles that treat scientific problems using methods that are of mathematical interest. Appropriate subject areas include the physical, engineering, financial, and life sciences. Examples are problems in fluid mechanics, including reaction-diffusion problems, sedimentation, combustion, and transport theory; solid mechanics; elasticity; electromagnetic theory and optics; materials science; mathematical biology, including population dynamics, biomechanics, and physiology; linear and nonlinear wave propagation, including scattering theory and wave propagation in random media; inverse problems; nonlinear dynamics; and stochastic processes, including queueing theory. Mathematical techniques of interest include asymptotic methods, bifurcation theory, dynamical systems theory, complex network theory, computational methods, and probabilistic and statistical methods.