Jetske van der Schaar, Leonie N.C. Visser, Femke H. Bouwman, Philip Scheltens, Annelien L. Bredenoord, Wiesje M. van der Flier
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Considerations regarding a diagnosis of Alzheimer’s Disease before dementia: a systematic review
Introduction The NIA-AA research framework proposes a purely biological definition of Alzheimer’s Disease (AD). This implies AD can be diagnosed based on biomarker abnormalities. While this brings opportunities, it also raises challenges.