钙通道Orai3参与非小细胞肺癌(NSCLC)顺铂化疗耐药

arXiv - QuanBio - Subcellular Processes Pub Date : 2023-07-18 DOI:arxiv-2307.10289

Rédoane Daoudi

{"title":"钙通道Orai3参与非小细胞肺癌(NSCLC)顺铂化疗耐药","authors":"Rédoane Daoudi","doi":"arxiv-2307.10289","DOIUrl":null,"url":null,"abstract":"This is the second part of the previous review. In the previous review we\nsuspected that Orai3 channels were involved in lung cancer and more precisely\nin several cancers. Here we confirm that calcium dysregulation is important for\ncancer development. in this paper we show that Orai3 is an upstream activator\nof AKT and we prove that AKT is involved in chemoresistance in NSCLC.","PeriodicalId":501170,"journal":{"name":"arXiv - QuanBio - Subcellular Processes","volume":"58 52","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Involvement of calcium channels Orai3 in the chemoresistance to cisplatin in non-small cell lung cancer (NSCLC)\",\"authors\":\"Rédoane Daoudi\",\"doi\":\"arxiv-2307.10289\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This is the second part of the previous review. In the previous review we\\nsuspected that Orai3 channels were involved in lung cancer and more precisely\\nin several cancers. Here we confirm that calcium dysregulation is important for\\ncancer development. in this paper we show that Orai3 is an upstream activator\\nof AKT and we prove that AKT is involved in chemoresistance in NSCLC.\",\"PeriodicalId\":501170,\"journal\":{\"name\":\"arXiv - QuanBio - Subcellular Processes\",\"volume\":\"58 52\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"arXiv - QuanBio - Subcellular Processes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/arxiv-2307.10289\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - QuanBio - Subcellular Processes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2307.10289","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

这是前面复习的第二部分。在之前的综述中，我们怀疑Orai3通道与肺癌有关，更确切地说，与几种癌症有关。在这里，我们证实钙失调对癌症的发展是重要的。在本文中，我们证明了Orai3是AKT的上游激活因子，并证明了AKT参与了NSCLC的化疗耐药。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Involvement of calcium channels Orai3 in the chemoresistance to cisplatin in non-small cell lung cancer (NSCLC)

This is the second part of the previous review. In the previous review we suspected that Orai3 channels were involved in lung cancer and more precisely in several cancers. Here we confirm that calcium dysregulation is important for cancer development. in this paper we show that Orai3 is an upstream activator of AKT and we prove that AKT is involved in chemoresistance in NSCLC.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

arXiv - QuanBio - Subcellular Processes

自引率

0.00%

发文量