Gideon Kofi Helegbe, Saeed Jabactey Abdullah, Baba Sulemana Mohammed
{"title":"血脂异常:加纳中低收入国家哺乳期妇女的患病率及相关因素","authors":"Gideon Kofi Helegbe, Saeed Jabactey Abdullah, Baba Sulemana Mohammed","doi":"10.1155/2023/6280494","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Dyslipidemia, an abnormally high level of lipids in the blood, has a negative impact on the health status of the individual and has lately emerged as a major public health concern, especially for low- and middle-income countries (LMIC) globally, including Ghana. However, it is still unclear what the burden and drivers of these lipid abnormalities are, especially among lactating women in the Upper West of Ghana. Thus, this study is aimed at determining the prevalence of dyslipidemia and its associated factors among lactating mothers in the Wa Municipality of Ghana. <i>Methodology</i>. A cross-sectional study was conducted from May to June 2020 in 8 health facilities within the Wa Municipality. Multistage and simple random sampling methods were used to select the facilities and the 200 study subjects. Sociodemographic data were collected using questionnaires, while blood samples were taken to determine the lipid profile of participants. Dietary patterns were also assessed using the Food Frequency Questionnaire (FFQ). Data were processed and analyzed using SPSS 17 software (SPSS, Inc., Chicago, IL). The chi-square test and multiple regression analysis were performed to determine the predictors associated with the various types of dyslipidemia, with statistical significance set at a <i>p</i> value < 0.05.</p><p><strong>Results: </strong>The prevalence of hypercholesterolemia (LDL-C), hypo-HDL-cholesterolemia, and hypertriglyceridemia (TG) was 57%, 59%, and 22%, respectively. Chi-square and multinomial regression analysis revealed that duration of lactation (<i>X</i><sup>2</sup> = 3.95, <i>p</i> = 0.047), religion (AOR = 0.375, 95% CI 0.144-0.978, <i>p</i> = 0.045), low income (AOR = 0.116, 95% CI 0.026-0.514, <i>p</i> = 0.005), middle income (AOR = 0.163, 95% CI 0.044-0.600, <i>p</i> = 0.006), and alcohol intake (AOR = 6.312, 95% CI 1.108-35.949, <i>p</i> = 0.038) were associated with LDL-C, while age (AOR = 0.963, 95% CI 0.910-1.019, <i>p</i> < 0.001) and educational status (AOR = 0.365, 95% CI 0.140-0.954, <i>p</i> = 0.040) predicted HDL status.</p><p><strong>Conclusion: </strong>Dyslipidemia is common among lactating mothers of Wa Municipality, and it is predicted by lifestyle factors. Furthermore, future research to look at a larger sample size on dyslipidemia during lactation is recommended.</p>","PeriodicalId":16274,"journal":{"name":"Journal of Lipids","volume":null,"pages":null},"PeriodicalIF":5.9000,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676279/pdf/","citationCount":"0","resultStr":"{\"title\":\"Dyslipidemias: Prevalence and Associated Factors among Lactating Women in a Lower- and Middle-Income Country, Ghana.\",\"authors\":\"Gideon Kofi Helegbe, Saeed Jabactey Abdullah, Baba Sulemana Mohammed\",\"doi\":\"10.1155/2023/6280494\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Dyslipidemia, an abnormally high level of lipids in the blood, has a negative impact on the health status of the individual and has lately emerged as a major public health concern, especially for low- and middle-income countries (LMIC) globally, including Ghana. However, it is still unclear what the burden and drivers of these lipid abnormalities are, especially among lactating women in the Upper West of Ghana. Thus, this study is aimed at determining the prevalence of dyslipidemia and its associated factors among lactating mothers in the Wa Municipality of Ghana. <i>Methodology</i>. A cross-sectional study was conducted from May to June 2020 in 8 health facilities within the Wa Municipality. Multistage and simple random sampling methods were used to select the facilities and the 200 study subjects. Sociodemographic data were collected using questionnaires, while blood samples were taken to determine the lipid profile of participants. Dietary patterns were also assessed using the Food Frequency Questionnaire (FFQ). Data were processed and analyzed using SPSS 17 software (SPSS, Inc., Chicago, IL). The chi-square test and multiple regression analysis were performed to determine the predictors associated with the various types of dyslipidemia, with statistical significance set at a <i>p</i> value < 0.05.</p><p><strong>Results: </strong>The prevalence of hypercholesterolemia (LDL-C), hypo-HDL-cholesterolemia, and hypertriglyceridemia (TG) was 57%, 59%, and 22%, respectively. Chi-square and multinomial regression analysis revealed that duration of lactation (<i>X</i><sup>2</sup> = 3.95, <i>p</i> = 0.047), religion (AOR = 0.375, 95% CI 0.144-0.978, <i>p</i> = 0.045), low income (AOR = 0.116, 95% CI 0.026-0.514, <i>p</i> = 0.005), middle income (AOR = 0.163, 95% CI 0.044-0.600, <i>p</i> = 0.006), and alcohol intake (AOR = 6.312, 95% CI 1.108-35.949, <i>p</i> = 0.038) were associated with LDL-C, while age (AOR = 0.963, 95% CI 0.910-1.019, <i>p</i> < 0.001) and educational status (AOR = 0.365, 95% CI 0.140-0.954, <i>p</i> = 0.040) predicted HDL status.</p><p><strong>Conclusion: </strong>Dyslipidemia is common among lactating mothers of Wa Municipality, and it is predicted by lifestyle factors. Furthermore, future research to look at a larger sample size on dyslipidemia during lactation is recommended.</p>\",\"PeriodicalId\":16274,\"journal\":{\"name\":\"Journal of Lipids\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2023-11-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676279/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Lipids\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/6280494\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Lipids","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2023/6280494","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:血脂异常,即血液中的脂质水平异常高,对个人的健康状况有负面影响,最近已成为一个主要的公共卫生问题,特别是在包括加纳在内的全球低收入和中等收入国家。然而,目前尚不清楚这些脂质异常的负担和驱动因素是什么,特别是在加纳上西部的哺乳期妇女中。因此,本研究旨在确定加纳瓦市哺乳期母亲中血脂异常的患病率及其相关因素。方法。2020年5月至6月,在Wa市的8个卫生设施中进行了一项横断面研究。采用多阶段、简单随机抽样的方法,选取设施和200名研究对象。通过问卷调查收集社会人口统计数据,同时采集血液样本以确定参与者的血脂状况。饮食模式也通过食物频率问卷(FFQ)进行评估。使用SPSS 17软件(SPSS, Inc., Chicago, IL)对数据进行处理和分析。采用卡方检验和多元回归分析确定与各类血脂异常相关的预测因素,p值< 0.05均有统计学意义。结果:高胆固醇血症(LDL-C)、低hdl -胆固醇血症和高甘油三酯血症(TG)的患病率分别为57%、59%和22%。卡方和多项式回归分析显示,哺乳时间(X2 = 3.95, p = 0.047),宗教(AOR = 0.375, 95% CI 0.144 - -0.978, p = 0.045),低收入(AOR = 0.116, 95% CI 0.026 - -0.514, p = 0.005),中等收入(AOR = 0.163, 95% CI 0.044 - -0.600, p = 0.006),和酒精摄入量(AOR = 6.312, 95% CI 1.108 - -35.949, p = 0.038)与低密度有关,而年龄(AOR = 0.963, 95% CI 0.910 - -1.019, p < 0.001)和教育状况(AOR = 0.365, 95% CI 0.140 - -0.954,p = 0.040)预测HDL水平。结论:瓦市哺乳期母亲血脂异常较为普遍,可通过生活方式因素进行预测。此外,建议今后对哺乳期血脂异常进行更大样本量的研究。
Dyslipidemias: Prevalence and Associated Factors among Lactating Women in a Lower- and Middle-Income Country, Ghana.
Background: Dyslipidemia, an abnormally high level of lipids in the blood, has a negative impact on the health status of the individual and has lately emerged as a major public health concern, especially for low- and middle-income countries (LMIC) globally, including Ghana. However, it is still unclear what the burden and drivers of these lipid abnormalities are, especially among lactating women in the Upper West of Ghana. Thus, this study is aimed at determining the prevalence of dyslipidemia and its associated factors among lactating mothers in the Wa Municipality of Ghana. Methodology. A cross-sectional study was conducted from May to June 2020 in 8 health facilities within the Wa Municipality. Multistage and simple random sampling methods were used to select the facilities and the 200 study subjects. Sociodemographic data were collected using questionnaires, while blood samples were taken to determine the lipid profile of participants. Dietary patterns were also assessed using the Food Frequency Questionnaire (FFQ). Data were processed and analyzed using SPSS 17 software (SPSS, Inc., Chicago, IL). The chi-square test and multiple regression analysis were performed to determine the predictors associated with the various types of dyslipidemia, with statistical significance set at a p value < 0.05.
Results: The prevalence of hypercholesterolemia (LDL-C), hypo-HDL-cholesterolemia, and hypertriglyceridemia (TG) was 57%, 59%, and 22%, respectively. Chi-square and multinomial regression analysis revealed that duration of lactation (X2 = 3.95, p = 0.047), religion (AOR = 0.375, 95% CI 0.144-0.978, p = 0.045), low income (AOR = 0.116, 95% CI 0.026-0.514, p = 0.005), middle income (AOR = 0.163, 95% CI 0.044-0.600, p = 0.006), and alcohol intake (AOR = 6.312, 95% CI 1.108-35.949, p = 0.038) were associated with LDL-C, while age (AOR = 0.963, 95% CI 0.910-1.019, p < 0.001) and educational status (AOR = 0.365, 95% CI 0.140-0.954, p = 0.040) predicted HDL status.
Conclusion: Dyslipidemia is common among lactating mothers of Wa Municipality, and it is predicted by lifestyle factors. Furthermore, future research to look at a larger sample size on dyslipidemia during lactation is recommended.
期刊介绍:
Journal of Lipids is a peer-reviewed, Open Access journal that publishes original research articles and review articles related to all aspects of lipids, including their biochemistry, synthesis, function in health and disease, and nutrition. As an interdisciplinary journal, Journal of Lipids aims to provide a forum for scientists, physicians, nutritionists, and other relevant health professionals.