在线干预解决老年艾滋病毒感染者心理健康问题的候补对照试验。

IF 1.3 4区 医学 Q4 INFECTIOUS DISEASES
Jeff Berko, Peter Mazonson, Duncan Short, Maile Karris, Lynsay Ehui, Cassidy A Gutner, Frank Spinelli, Andrew Zolopa
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引用次数: 0

摘要

背景:老年艾滋病毒感染者(PLWH)经常经历高水平的抑郁、焦虑和孤独。方法:这项候补对照试验检验了在线音频正念课程对老年PLWH患者这些感受的影响。结果:在214名参与者中,平均(SD)年龄为60.4(5.9)岁,89%为男性,69%为白人。25天后,干预组在抑郁症状(改善20.3%,p < 0.01)和焦虑症状(改善22.4%,p = 0.03)方面与等候名单对照组相比有显著改善,但在每日日记(改善12.9%,p = 0.07)或3项孤独量表(改善4.8%,p = 0.27)方面没有改善。在基线抑郁症状升高的参与者中进行的二次分析显示改善26.3% (p < 0.01),具有中等效应大小(Hedge’s g = 0.69)。同样,焦虑基线症状升高的患者表现出25.6%的改善(p < 0.01),中等效应量(g = 0.54),而孤独感中度或重度升高的患者表现出18.9%的日常孤独感改善(p < 0.01),中等效应量(g = 0.55)。结论:这项候补对照试验首次表明,一系列简短的在线音频正念课程可以改善老年PLWH患者的心理健康状况。对于许多患者来说,这种干预可能提供既容易获得又负担得起的缓解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Waitlist-controlled trial of an online intervention to address mental health among older people living with HIV.

Background: Older people living with HIV (PLWH) often experience elevated levels of depression, anxiety, and loneliness.Methods: This waitlist-controlled trial examined the effectiveness of online audio mindfulness lessons in impacting these feelings among older PLWH.Results: Among 214 participants, the mean (SD) age was 60.4 (5.9) years, 89% were male, and 69% were white. After 25 days, the intervention group showed significant improvements versus the waitlist control group in symptoms of depression (20.3% improvement, p < .01) and symptoms of anxiety (22.4% improvement, p = .03), but not in loneliness as measured by a Daily Diary (12.9% improvement, p = .07) or the 3-Item Loneliness Scale (4.8% improvement, p = .27). Secondary analyses among participants with elevated baseline symptoms of depression showed a 26.3% improvement (p < .01), with a moderate effect size (Hedge's g = 0.69). Similarly, those with elevated baseline symptoms of anxiety showed a 25.6% improvement (p < .01), a moderate effect size (g = 0.54), while those with moderate or severely elevated loneliness showed an 18.9% improvement in daily loneliness (p < .01), a moderate effect size (g = 0.55).Conclusion: This waitlist-controlled trial is the first to show that a series of brief, online audio mindfulness lessons improves mental health outcomes among older PLWH. For many patients, this intervention may offer relief that is both accessible and affordable.

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来源期刊
Antiviral Therapy
Antiviral Therapy 医学-病毒学
CiteScore
2.60
自引率
8.30%
发文量
35
审稿时长
4-8 weeks
期刊介绍: Antiviral Therapy (an official publication of the International Society of Antiviral Research) is an international, peer-reviewed journal devoted to publishing articles on the clinical development and use of antiviral agents and vaccines, and the treatment of all viral diseases. Antiviral Therapy is one of the leading journals in virology and infectious diseases. The journal is comprehensive, and publishes articles concerning all clinical aspects of antiviral therapy. It features editorials, original research papers, specially commissioned review articles, letters and book reviews. The journal is aimed at physicians and specialists interested in clinical and basic research.
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