{"title":"高免疫球蛋白E综合征。","authors":"R S Geha, D Y Leung","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The Hyper Immunoglobulin E(HIE) Syndrome is a rare disorder of unknown etiology associated with extremely high serum IgE levels, serious recurrent infections and chronic dermatitis. The current paper will review the clinical and laboratory manifestations of the HIE Syndrome and discuss them in relationship to underline immunologic abnormalities found in this syndrome.</p>","PeriodicalId":77170,"journal":{"name":"Immunodeficiency reviews","volume":"1 2","pages":"155-72"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hyper immunoglobulin E syndrome.\",\"authors\":\"R S Geha, D Y Leung\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Hyper Immunoglobulin E(HIE) Syndrome is a rare disorder of unknown etiology associated with extremely high serum IgE levels, serious recurrent infections and chronic dermatitis. The current paper will review the clinical and laboratory manifestations of the HIE Syndrome and discuss them in relationship to underline immunologic abnormalities found in this syndrome.</p>\",\"PeriodicalId\":77170,\"journal\":{\"name\":\"Immunodeficiency reviews\",\"volume\":\"1 2\",\"pages\":\"155-72\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunodeficiency reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunodeficiency reviews","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Hyper Immunoglobulin E(HIE) Syndrome is a rare disorder of unknown etiology associated with extremely high serum IgE levels, serious recurrent infections and chronic dermatitis. The current paper will review the clinical and laboratory manifestations of the HIE Syndrome and discuss them in relationship to underline immunologic abnormalities found in this syndrome.
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