鼻息肉的外科治疗与内科治疗。

Rhinology. Supplement Pub Date : 1989-01-01
T Lildholdt
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引用次数: 0

摘要

手术切除鼻息肉会给患者带来不适和风险,但这是大多数耳鼻喉科医生的治疗选择。仅药物治疗方面的研究很少。在一项前瞻性临床试验中,手术切除后持续局部类固醇治疗与单剂量类固醇沉积后持续局部类固醇治疗进行了比较。在为期一年的研究期间,监测了呼气鼻峰流量和嗅觉。总的来说,两组的病程相似,倾向于接受药物治疗的组。在另一项研究中,通过实验进一步证明了这种医疗方案的临床疗效。在注射类固醇沉积液前和注射后几天,用声鼻测量法测量鼻道的平方面积。发现体积增加,对应于立即临床改善。结论鼻息肉的初步治疗应以药物为主。只有在药物治疗无效的情况下才建议进行手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical versus medical treatment of nasal polyps.

Surgical removal of nasal polyps is associated with discomfort and risks for the patient, but is the treatment of choice to most otorhinolaryngologists. Medical treatment alone has been little investigated. In a prospective clinical trial surgical removal followed by continuous topical steroid treatment has been compared with a single dose of steroid deposit followed by continuous topical steroid treatment. During a study period of one year, expiratory nasal peak flow and sense of smell were monitored. In general, the course in the two groups was alike, with a tendency favouring the medically treated group. In another study the clinical efficacy of this medical regimen was further documented experimentally. By acoustic rhinometry the square area of the nasal passages was measured before and a few days after the injection of the steroid deposit. Increased volume was found, corresponding to the instant clinical improvement. It is concluded that primary treatment of nasal polyps should be medical. Surgery is only recommended in cases, resistant to medical therapy.

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