Growth in the myopathic Syrian hamster (Cricetus auratus).

The objective was to assess the effect of the hereditary myopathic disease (muscular dystrophy) on 4 growth parameters: body-weight, head-body length, skull weight and cranial length in the Syrian hamster over a 4-13 month period. A control colony of 34 males and 32 females was compared to a muscular dystrophy colony consisting of 37 males and 27 females. The monthly means of the 4 growth parameters were computed and full data were used for computations of analysis of variance with regression of each group, sex and growth parameter. Intersex and intergroup comparisons of the same parameters were made using analysis of covariance. In the controls, the male bodies were heavier and longer than the female bodies; males grew over the total period. In dystrophic hamsters, males were heavier than females, but females were longer. In both control and dystrophic hamsters, female skulls were longer and heavier. In all parameters the means of the control colony were greater than those of the dystrophic colony relative to age. The disease factor in the muscular dystrophy colony adversely influenced all 4 growth parameters.