{"title":"类活化血管病","authors":"María del Carmen Fernández-Antón Martínez","doi":"10.1016/j.semreu.2010.11.001","DOIUrl":null,"url":null,"abstract":"<div><p>Livedoid vasculopathy is a rare disease characterized by chronic, painful ulceration of the lower limbs that tends to progress to white atrophic lesions (atrophie blanche). These lesions are not pathognomonic but are the result of multiple processes. Livedoid vasculopathy is much more common in females, and usually occurs bilaterally in the distal third of the lower extremities.</p><p>Diagnosis is not easy and is often not made until the disease has progressed. Consequently clinical and pathological correlation is required to suspect this entity. Biopsy of skin lesions aids diagnosis, but lacks pathognomonic findings. A broad therapeutic arsenal is available, which should be assessed individually according to the characteristics of each patient.</p></div>","PeriodicalId":101152,"journal":{"name":"Seminarios de la Fundación Espa?ola de Reumatología","volume":"12 2","pages":"Pages 53-56"},"PeriodicalIF":0.0000,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.semreu.2010.11.001","citationCount":"0","resultStr":"{\"title\":\"Vasculopatía livedoide\",\"authors\":\"María del Carmen Fernández-Antón Martínez\",\"doi\":\"10.1016/j.semreu.2010.11.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Livedoid vasculopathy is a rare disease characterized by chronic, painful ulceration of the lower limbs that tends to progress to white atrophic lesions (atrophie blanche). These lesions are not pathognomonic but are the result of multiple processes. Livedoid vasculopathy is much more common in females, and usually occurs bilaterally in the distal third of the lower extremities.</p><p>Diagnosis is not easy and is often not made until the disease has progressed. Consequently clinical and pathological correlation is required to suspect this entity. Biopsy of skin lesions aids diagnosis, but lacks pathognomonic findings. A broad therapeutic arsenal is available, which should be assessed individually according to the characteristics of each patient.</p></div>\",\"PeriodicalId\":101152,\"journal\":{\"name\":\"Seminarios de la Fundación Espa?ola de Reumatología\",\"volume\":\"12 2\",\"pages\":\"Pages 53-56\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.semreu.2010.11.001\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminarios de la Fundación Espa?ola de Reumatología\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1577356611000091\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminarios de la Fundación Espa?ola de Reumatología","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1577356611000091","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Livedoid vasculopathy is a rare disease characterized by chronic, painful ulceration of the lower limbs that tends to progress to white atrophic lesions (atrophie blanche). These lesions are not pathognomonic but are the result of multiple processes. Livedoid vasculopathy is much more common in females, and usually occurs bilaterally in the distal third of the lower extremities.
Diagnosis is not easy and is often not made until the disease has progressed. Consequently clinical and pathological correlation is required to suspect this entity. Biopsy of skin lesions aids diagnosis, but lacks pathognomonic findings. A broad therapeutic arsenal is available, which should be assessed individually according to the characteristics of each patient.