更昔洛韦治疗一例肾移植受者巨细胞病毒视网膜炎。

I H Horng, M S Chen, P H Lee, Y C Chen, C S Lee, P K Hou
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引用次数: 0

摘要

巨细胞病毒性视网膜炎是免疫抑制患者的机会性和视力威胁疾病。目前可用的抗病毒药物未能阻止其发展。我们报告一例巨细胞病毒视网膜炎,发生在肾移植后6个月,通过静脉给药更昔洛韦(DHPG[二羟基丙氧甲基鸟嘌呤],Cytovene, BW-B759U)成功治疗,活性视网膜病变消退,尿液中巨细胞病毒脱落停止。在静脉注射更昔洛韦治疗后9个月的随访中,没有发生巨细胞病毒性视网膜炎复发或视网膜脱离。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cytomegalovirus retinitis treated with ganciclovir in a renal transplant recipient.

Cytomegalovirus retinitis is an opportunistic and vision-threatening disease in immunosuppressed patients. Currently available antiviral agents have been unsuccessful in halting its progression. We report a case of cytomegalovirus retinitis which occurred 6 months after renal transplantation and was successfully treated with an investigational drug, ganciclovir (DHPG [Dihydroxy propoxymethyl guanine], Cytovene, BW-B759U), via intravenous administration, with resolution of active retinal lesions and the cessation of cytomegalovirus shedding in the urine. There was neither a recurrence of cytomegalovirus retinitis nor an occurrence of retinal detachment during the 9-month follow-up after intravenous ganciclovir therapy.

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