Michelle Lilly Rojas Arellano , Víctor Hugo Carmona Ornelas , Mauro García Bahena , Sergio Bruno Muñoz Cortés , Ángel Augusto Pérez-Calatayud
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Coriocarcinoma durante la perimenopausia: reporte de un caso
Introduction
There are few cases reported in the literature on gestational trophoblastic disease in postmenopausal women, and there are even fewer reports of choriocarcinoma at this stage. The case is presented of a patient diagnosed with uterine choriocarcinoma, whose last obstetrical event was 14 years before the current condition.
Conclusions
Studies of DNA microsatellite polymorphism are the most specific to confirm gestational tumour origin. Pulsatility index of the uterine artery used as a predictor of resistance to methotrexate, first-line drug in the treatment of this cancer, is currently being studied.