[一些罕见形式胰腺肿瘤的临床和治疗方面]。

M Chifan, V Strat, E Tîrcoveanu, D Niculescu, S Georgescu, G Dobrescu, N Florea, C Stanciu
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引用次数: 0

摘要

1972年至1987年期间,共有198例胰腺肿瘤在贾西第一外科诊所住院治疗。这些肿瘤中只有10个是良性的,包括:2个胃腺瘤、2个胰岛素瘤、2个囊腺瘤、1个纤维脂肪瘤、1个淋巴管瘤、1个水疱和1个Wermer综合征。分析了这10例胰腺良性肿瘤的特点,并强调大多数临床和治疗问题是由内分泌胰腺肿瘤决定的,特别是那些激素活跃的肿瘤。因此,这些难以评估的肿瘤的症状学,特别是在症状开始时,将决定手术诊断的相当延迟,许多患者在到达外科医生之前在其他部门住院。目前诊断和治疗的可能性与调查领域取得的进展保持同步,从形态学和功能的角度提供了有用的数据。以上10例均受益于手术治疗,手术治疗根据患者的具体情况进行调整。作者强调了临时形态学-组织学检查(连续切片)的重要性,当肿瘤难以通过直接宏观检查识别时,他们建议术中超声检查和术前和术中门静脉循环样本的直接激素剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Clinical and therapeutic aspects of some rare forms of pancreatic tumors].

A total of 198 tumours of the pancreas have been hospitalized between 1972 and 1987 in the 1st Surgical Clinic from Jassy. Only 10 of these tumours were benign, and these included: 2 gastrinomas, 2 insulinomas, 2 cystadenomas, one fibrolipoma, 1 lymphangioma, one hydatic cyst and a Wermer's syndrome. The particularities are analysed, of these 10 cases of benign tumours of the pancreas, and it is stressed that most of the clinical and therapeutic problems are determined by tumours of the endocrine pancreas, and especially those which are hormonally active. Thus the symptomatology of these last tumours which is difficult to evaluate, especially at the onset of the symptoms will determine a considerable delay in the surgical diagnosis, many of the patients being hospitalized in other departments before reaching the surgeon. Present possibilities for diagnosis and treatment have kept pace with progresses achieved in the field of investigations, which provide useful data from the morphological and functional viewpoints. All the 10 cases mentioned above have benefited from the surgical treatment, that was adapted according to particularities of each patient. The authors stress the importance of the extemporaneous morpho-histologic examination (with serial slides) and when the tumours are difficult to identify by direct macroscopic examination they recommend intraoperative echography and direct hormonal dosages on samples obtained from the portal circulation before and during surgery.

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