{"title":"小儿胃食管反流","authors":"P. Molkhou","doi":"10.1016/j.emcped.2005.03.002","DOIUrl":null,"url":null,"abstract":"<div><p>The clinical manifestations of gastroesophageal reflux (GER) in infancy and childhood include vomiting dysphagia, abdominal pain and substernal pain, oesophagitis and respiratory disorders. Diagnostic approaches consist of history and physical examination, oesophageal pH monitoring, endoscopy, biopsy and sometimes an empiric medical therapy. Treatment options in infancy include prone position, diet change with milk thickening agents, and if necessary with a new formula without cow milk proteins. Lifestyle changes are recommended. In case of oesophagitis, acid suppressor therapy with proton pump inhibitors are used. Prokinetic therapy reduces the frequency of symptoms. Surgical therapy (fundoplication) generally results in favourable outcomes in case of prolonged medical therapy failure.</p></div>","PeriodicalId":100441,"journal":{"name":"EMC - Pédiatrie","volume":"2 2","pages":"Pages 196-209"},"PeriodicalIF":0.0000,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emcped.2005.03.002","citationCount":"0","resultStr":"{\"title\":\"Reflux gastro-œsophagien chez l'enfant\",\"authors\":\"P. Molkhou\",\"doi\":\"10.1016/j.emcped.2005.03.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The clinical manifestations of gastroesophageal reflux (GER) in infancy and childhood include vomiting dysphagia, abdominal pain and substernal pain, oesophagitis and respiratory disorders. Diagnostic approaches consist of history and physical examination, oesophageal pH monitoring, endoscopy, biopsy and sometimes an empiric medical therapy. Treatment options in infancy include prone position, diet change with milk thickening agents, and if necessary with a new formula without cow milk proteins. Lifestyle changes are recommended. In case of oesophagitis, acid suppressor therapy with proton pump inhibitors are used. Prokinetic therapy reduces the frequency of symptoms. Surgical therapy (fundoplication) generally results in favourable outcomes in case of prolonged medical therapy failure.</p></div>\",\"PeriodicalId\":100441,\"journal\":{\"name\":\"EMC - Pédiatrie\",\"volume\":\"2 2\",\"pages\":\"Pages 196-209\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.emcped.2005.03.002\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EMC - Pédiatrie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1762601305000066\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EMC - Pédiatrie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1762601305000066","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The clinical manifestations of gastroesophageal reflux (GER) in infancy and childhood include vomiting dysphagia, abdominal pain and substernal pain, oesophagitis and respiratory disorders. Diagnostic approaches consist of history and physical examination, oesophageal pH monitoring, endoscopy, biopsy and sometimes an empiric medical therapy. Treatment options in infancy include prone position, diet change with milk thickening agents, and if necessary with a new formula without cow milk proteins. Lifestyle changes are recommended. In case of oesophagitis, acid suppressor therapy with proton pump inhibitors are used. Prokinetic therapy reduces the frequency of symptoms. Surgical therapy (fundoplication) generally results in favourable outcomes in case of prolonged medical therapy failure.